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Research Highlights

Recent publications

Dombrowski C, Cisneros L, Chatkaew S, Goldstein RE, Kessler JO. 2004 Aug. Self-concentration and large-scale coherence in bacterial dynamics. Phys Rev Lett 93:098103

Wolgemuth CW, Goldstein RE, Powers TR. 2004 May. Dynamic Supercoiling Bifurcations of Growing Elastic Filaments. Physica D 190:266-289

Dombrowski C, Cisneros L, Chatkaew S, Goldstein RE, Kessler JO. 2004 Aug. Self-concentration and large-scale coherence in bacterial dynamics. Phys Rev Lett 93:098103

Maggiora, G.M. (2002). Computer-Aided Decision Making in Pharmaceutical Research.. In Proceedings of 2002 Beilstein Workshop on Molecular Informatics: Confronting Complexity, Martin Hicks & C. Kettner, Eds., held in Bolzano, Italy, May 13-16, 2002, pp. 149-166.

Maggiora, G.M. and Shanmugasundaram, V. (2004). Molecular Similarity Measures. In Chemoinformatics: Concepts, Methods, and Tools for Drug Discovery, J. Bajorath, Ed., Humana Press, Totowa, New Jersey, pp. 1-50.

Maggiora, G.M., Shanmugasundaram, V., Lajiness, M.S., Doman, T.N., and Schulz, M.W. (2004). .A Practical Strategy for Directed Compound Acquisition. In Cheminformatics Aspects in Drug Discovery, T. Oprea, Ed., Wiley-VCH, New York, in press.

Weichsel A, Maes EM, Andersen JF, Valenzuela JG, Shokhireva TKh, Walker FA, Montfort WR. 2005 Jan. Heme-assisted S-nitrosation of a proximal thiolate in a nitric oxide transport protein. Proc Natl Acad Sci U S A 102:594-9

Jarmula A, Cieplak P, Montfort WR. 2005 Feb. 5,10-Methylene-5,6,7,8-tetrahydrofolate conformational transitions upon binding to thymidylate synthase: molecular mechanics and continuum solvent studies. J Comput Aided Mol Des 19:123-36

Loftin IR, Franke S, Roberts SA, Weichsel A, Heroux A, Montfort WR, Rensing C, McEvoy MM. 2005 Aug. A novel copper-binding fold for the periplasmic copper resistance protein CusF. Biochemistry 44:10533-40

Maes EM, Weichsel A, Andersen JF, Shepley D, Montfort WR. 2004 Jun. Role of binding site loops in controlling nitric oxide release: structure and kinetics of mutant forms of nitrophorin 4. Biochemistry 43:6679-90

Baker KE, Coller J, Parker R. 2004 Jul. The yeast Apq12 protein affects nucleocytoplasmic mRNA transport. RNA2004 Jul 23;

Coller J, Parker R. 2004 Jan. Eukaryotic mRNA decapping. Annu Rev Biochem 73:861-90

Baker KE, Parker R. 2004 Jun. Nonsense-mediated mRNA decay: terminating erroneous gene expression. Curr Opin Cell Biol 16:293-9

Pries AR, Secomb TW. 2005 Mar. Control of blood vessel structure: insights from theoretical models. Am J Physiol Heart Circ Physiol 288:H1010-5

Gruionu G, Hoying JB, Gruionu LG, Laughlin MH, Secomb TW. 2005 Jan. Structural adaptation increases predicted perfusion capacity following vessel obstruction in the arteriolar arcade network of pig skeletal muscle. Am J Physiol Heart Circ Physiol2005 Jan 28;

Pries AR, Secomb TW. 2005 Jul. Microvascular blood viscosity in vivo and the endothelial surface layer. Am J Physiol Heart Circ Physiol2005 Jul 22;

El-Kareh AW, Secomb TW. 2005 Jul. Two-mechanism peak concentration model for cellular pharmacodynamics of Doxorubicin. Neoplasia 7:705-13

Goriely A, Tabor M. 2003 May. Biomechanical models of hyphal growth in actinomycetes. J Theor Biol 222:211-8

Goriely A, Tabor M. 2003 Mar. Self-similar tip growth in filamentary organisms. Phys Rev Lett 90:108101

Walsh B, Henderson D. 2004 Jan. Microarrays and beyond: what potential do current and future genomics tools have for breeders?. J Anim Sci 82 E-Suppl:E292-299

Walsh B. 2003 Jul. Population-genetic models of the fates of duplicate genes. Genetica 118:279-94

Walsh B. 2001 May. Quantitative genetics in the age of genomics. Theor Popul Biol 59:175-84

Joseph C. Watkins (2004) The Role of Marriage Rules in the Structure of Genetic Relatedness, Theoretical Population Biology 66, 13-24

J.S. Lansing, A.J. Redd, T. M. Karafet, J.Watkins, I.W. Ardika, S.P.K. Surata, J.S. Schoenfelder, M. Campbell, A.M. Merriwether, M.F. Hammer (2004) An Indian Trader in Ancient Bali? Antiquity 78

Tatiana M. Karafet, J. S. Lansing, Alan J. Redd, Joseph Watkins, I. W. Ardika, S. P.K. Surata, Laura Mayer, Michael Bamshad, Lynn Jorde, Michael F. Hammer (2005) Balinese Y Chromosome Perspective on the Peopling of Indonesia: Genetic Contributions from Pre-Neolithic Hunter-Gatherers, Austronesian Farmers, and Indian Traders, Human Biology 77.1, 93-114

Ma, W., Li, G., Zohar, Y. and Wong, M., Fabrication and packaging of inertia micro-switch using low temperature photo-resist molded metal-electroplating technology. Sensors and Actuators A, 111, 63-70, 2004

Ng, A.S.W., Hau, W.L.W., Lee, Y.K. and Zohar, Y., Electrokinetic generation of micro vortex patterns in a microchannel liquid flow. J. Micromech. Microeng., 14, 247-255, 2004