Qureshi, A. I., Palesch, Y. Y., Barsan, W. G., Hanley, D. F., Hsu, C. Y., Martin, R. L., Moy, C. S., Silbergleit, R., Steiner, T., Suarez, J. I., Toyoda, K., Wang, Y., Yamamoto, H., & Yoon, B. W. (2016). Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage. The New England journal of medicine, 375(11), 1033-43.
BIO5 Collaborators
Kurt R Denninghoff, Chelsea Kidwell
Background Limited data are available to guide the choice of a target for the systolic blood-pressure level when treating acute hypertensive response in patients with intracerebral hemorrhage. Methods We randomly assigned eligible participants with intracerebral hemorrhage (volume,
Menon, R., & Kidwell, C. (2013). Reply: To PMID 22367992. Annals of neurology, 73(6), 797.
Kidwell, C. S., Rosand, J., Norato, G., Dixon, S., Worrall, B. B., James, M. L., Elkind, M. S., Flaherty, M. L., Osborne, J., Vashkevich, A., Langefeld, C. D., Moomaw, C. J., & Woo, D. (2017). Ischemic lesions, blood pressure dysregulation, and poor outcomes in intracerebral hemorrhage. Neurology, 88(8), 782-788.
To evaluate the associations among diffusion-weighted imaging (DWI) lesions, blood pressure (BP) dysregulation, MRI markers of small vessel disease, and poor outcome in a large, prospective study of primary intracerebral hemorrhage (ICH).
Woo, D., Rosand, J., Kidwell, C., McCauley, J. L., Osborne, J., Brown, M. W., West, S. E., Rademacher, E. W., Waddy, S., Roberts, J. N., Koch, S., Gonzales, N. R., Sung, G., Kittner, S. J., Birnbaum, L., Frankel, M., Testai, F. D., Hall, C. E., Elkind, M. S., , Flaherty, M., et al. (2013). The Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study protocol. Stroke, 44(10), e120-5.
Epidemiological studies of intracerebral hemorrhage (ICH) have consistently demonstrated variation in incidence, location, age at presentation, and outcomes among non-Hispanic white, black, and Hispanic populations. We report here the design and methods for this large, prospective, multi-center case-control study of ICH.
Nael, K., Trouard, T. P., Lafleur, S. R., Krupinski, E. A., Salamon, N., & Kidwell, C. S. (2015). White matter ischemic changes in hyperacute ischemic stroke: voxel-based analysis using diffusion tensor imaging and MR perfusion. Stroke; a journal of cerebral circulation, 46(2), 413-8.
The purpose of this study was to evaluate changes in fractional anisotropy (FA), as measured by diffusion tensor imaging, of white matter (WM) infarction and hypoperfusion in patients with acute ischemic stroke using a quantitative voxel-based analysis.
