Dagne, E., Gunatilaka, A., Asmellash, S., Abate, D., Kingston, D. G., Hofmann, G. A., & Johnson, R. K. (1994). Two new cytotoxic cytochalasins from Xylaria obovata. Tetrahedron, 50(19), 5615-5620.
Abstract:
Two new cytotoxic cytochalasins were isolated by brine shrimp bioassay-guided fractionation from a culture of the wood inhabiting fungus, Xylaria obovata. Their structures were determined as 19,20-epoxycytochalasin Q (1) and its deacetyl analog 2 by the application of spectroscopic techniques and chemical correlation with cytochalasin R. Acetylation of 2 yielded 1. Both 1 and 2 were cytotoxic but were found to be inactive in an HIV-protease inhibitory assay and a mechanism-based DNA damaging yeast assay. © 1994.
Herz, J. E., Torres, J. V., Murillo, A., Cruz, S., Shafiee, A., Vosooghi, M., Sotheeswaran, S., & Gunatilaka, A. A. (1985). Potential long-acting contraceptive agents: Esters and ethersof testosterone with α-and/or β-chain branching. Steroids, 46(6), 947-953.
PMID: 3842023;Abstract:
The synthesis of ten esters and two ethers of testosterone (17 β-hydroxyandrost-4-en-3-one) is described. All these possess some form of α-and/or β-substitution in the ester/ether sidechain. The work was undertaken in order to evaluate the long-acting antifertility effect of such compounds in males. © 1985.
Gunatilaka, L., Tillotson, J., Bashyal, B. P., Kang, M., Shi, T., Cruz, F. D., & Chapman, E. (2016). Selective inhibition of p97 by chlorinated analogues of dehydrocurvularin. Organic & Biomolecular Chemistry, 14, 5918-5921.
Gunatilaka, A. L. (1998). Chapter 1 Alkaloids From Sri Lankan Flora*. Alkaloids: Chemistry and Biology, 52(C), 1-101.
Gunatilaka, A. L., & Sotheeswaran, S. (1978). Convenient preparation of esters of testosterone and 19-norethisterone with hindered acids. Journal of the Chemical Society, Chemical Communications, 980-981.
Abstract:
Testosterone and 19-norethisterone are smoothly esterified by some hindered carboxylic acids in pyridine containing benzenesulphonyl chloride.