Professor, Applied Mathematics - GIDP, Professor, BIO5 Institute, Professor, Chemistry and Biochemistry-Sci
Research Professor, Research Professor, BIO5 Institute
Peptides and proteins play a vital role in almost every cellular process in living organisms. Our research discovers and determines structural information on peptides and proteins to design drugs to more effectively treat human disease.
Associate Professor, Genetics - GIDP, Associate Professor, Molecular and Cellular Biology, Associate Professor, BIO5 Institute
Assistant Professor, BIO5 Institute, Assistant Professor, Chemistry and Biochemistry
Andrew Hausrath's lab studies the structures of proteins and complexes using X-ray crystallography, microscopy, and biophysical techniques. Proteins of certain classes are heavily represented as components of complexes. Knowledge of the structures and properties of the proteins which function within higher-order complexes then stimulates development of improved models and theory about how such complexes carry out their functions in the cell. Systems of current interest include the ATP synthase, the signaling hormone adiponectin, and the higher-order organization of chromatin in the nucleus.
Associate Director, Shared Resources, Associate Professor, Pharmacology, Director, Aribi Institute, Professor, BIO5 Institute, Professor, Biomedical Engineering, Professor, Physiological Sciences - GIDP, Professor, Physiology
Precise diagnosis and treatment of disease requires an ability to target agents to specific tissues and cell types within those tissues. We are developing agents that exhibit cell type specificity for these purposes.
Interim Associate Department Head, Research/Faculty Affairs, Professor, BIO5 Institute, Professor, Chemistry and Biochemistry, Professor, Chemistry and Biochemistry-Sci, Professor, Immunobiology
How we sense and react to our environment is communicated in the cell by vast networks of highly dynamic, interacting proteins. These interactions are regulated in both space and time, and it is this tight regulation that allows signals from outside of the cell to be rapidly and precisely transmitted to the nucleus leading to the appropriate, and healthy, cellular response. My research integrates structural biology, biophysics and biochemistry in order to understand how these signals and to develop novel drugs for the treatment of cancer, autoimmune disorders and antibiotic resistance. Lab website: https://sites.google.com/view/pagelaboratory