Professor, Pathology - (Research Scholar Track), Research Professor, BIO5 Institute
Professor, Immunobiology , Member of the Graduate Faculty
Cancer models have been utilized to define properties of the anti-tumor response and factors that regulate the function of distinct cellular populations. The overarching results highlight the importance of the Wnt signaling pathways that utilize the canonical pathways but also new pathways that don‚Äôt utilize the canonical pathways. These pathways may also be significantly impacted by Notch signaling. Novel cellular functions have been identified and the hope is that it will lead to innovative therapeutic approaches to treat cancer. In addition, studies of the Wnt antagonist DKK1 in the chronic parasitic infections by Leishmania major are being utilized to define the primary mechanistic interactions that lead to the infections.
Associate Professor, Immunobiology, Associate Professor, Molecular and Cellular Biology, Associate Professor, Cancer Biology - GIDP, Associate Professor, BIO5 Institute
We aim to understand the mechanisms of HPV infection, the cellular responses to HPV infection, and how the interplay between host and virus influences the outcome
Director, Cutaneous Oncology Program, Division Chief, Dermatology, Member of the Graduate Faculty, Professor, BIO5 Institute, Professor, Medicine - (Tenure Track)
Specialist, Embryonic Stem Cell Culture, Member of the General Faculty
I am investigating a human connective tissue disorder in mice. I am also investigating the role of gut bacteria in colon cancer risk in both a mouse model of colon cancer and in humans with colon cancer.
Professor, Medicine, Professor, Nutritional Sciences, Professor, Cancer Biology - GIDP, Professor, Physiological Sciences - GIDP, Clinical Instructor, Pharmacy Practice-Science, Member of the Graduate Faculty, Professor, BIO5 Institute
Janet Funk's work includes a focus on metastatic breast cancer that spans the research spectrum from bench to bedside, translational arthritis studies of the pharmacokinetics and safety of turmeric, and collaborative endocrinological studies evaluating the effects of obesity and insulin resistance on bone development in Hispanic girls, as well as effects of obesity on breast cancer risk in older women.
Assistant Research Scientist, Cancer Center Division, Associate Professor, BIO5 Institute, Investigator, Center for Toxicology, Professor, Pharmacology and Toxicology, Professor, Cancer Biology - GIDP
Bernard Futscher's lab is studying the molecular origins of human cancer. Understanding epigenetic dysfunction in human cancer has been Dr. Futscher's primary research focus since establishing his own independent laboratory. This epigenetic research has moved into the area of noncoding RNAs and their potential role in cancer cell immortality.
Associate Professor, Animal and Comparative Biomedical Sciences, Associate Professor, BIO5 Institute
Director, Biostatistics - Phoenix Campus, Professor, Public Health, Professor, Statistics-GIDP, Professor, BIO5 Institute
Chengcheng Hu has worked on a broad range of areas including cancer, occupational health, HIV/AIDS, and aging. He has extensive collaborative research in conducting methodological research in the areas of survival analysis, longitudinal data, high-dimensional data, and measurement error. His current methodological interest, arising from studies of viral and human genetics and biomarkers, is to develop innovative methods to investigate the relationship between high-dimensional information and longitudinal outcomes or survival endpoints.
Professor, Nutritional Sciences, Professor, Cancer Biology - GIDP, Professor, Physiological Sciences - GIDP, Assistant Dean, Graduate Education, Professor, BIO5 Institute
Kirsten Limesand's research program has its foundation in radiation-induced salivary gland dysfunction; mechanisms of damage, clinical prevention measures, and restoration therapies. They utilize a number of techniques including: genetically engineered mouse models, real-time RT/PCR, immunoblotting, immunohistochemistry, primary cultures, siRNA transfections, and procedures to quantitate salivary gland physiology and integrate this information in order to understand the complete system.
Associate Professor, Chemistry and Biochemistry-Sci, Associate Professor, BIO5 Institute
We seek to produce new drugs that harness molecules produced during the natural immune response in order to treat cancer and pain. Such compounds may also provide new treatments for heart failure and alcoholism.
Professor, Cellular and Molecular Medicine, Chair, Cancer Biology - GIDP, Co-Program Leader, Cancer Biology Research Program, Member of the Graduate Faculty, Professor, BIO5 Institute
Professor, Nutritional Sciences, Associate, Center for Toxicology, Professor, Animal and Comparative Biomedical Sciences, Professor, Cancer Biology - GIDP, Professor, BIO5 Institute
Associate Professor, Pathology - (Research Scholar Track), Associate Professor, Applied BioSciences - GIDP, Associate Professor, BIO5 Institute
We are studying how tumor cells escape immunosurveillance, a hallmark of cancer, in aggressive lymphomas. MHCII is a protein important for immunosurveillance. We are studying the underlying mechanisms of altered regulation of MHCII in lymphoma cells and its effects on tumor immunosurveillance.
Professor, Molecular and Cellular Biology, Department Head, Molecular and Cellular Biology, Professor, Cancer Biology - GIDP, Professor, Genetics - GIDP, Professor, BIO5 Institute
Director, Canyon Ranch Center for Prevention and Health Promotion, Professor, Public Health, Distinguished Professor, Professor, Clinical Translational Sciences, Professor, Medicine, Professor, Nutritional Sciences Graduate Program, Professor, BIO5 Institute
Assistant Professor, Cellular and Molecular Medicine, Assistant Professor, BIO5 Institute
We combine chemical and computer vision approaches to discover how regenerative tissues process environmental information to promote accurate cell fate decisions and prevent uncontrolled cell growth.