Professor, BIO5 Institute, Professor, Immunobiology
Associate Professor, Animal and Comparative Biomedical Sciences, Associate Professor, Plant Sciences
We are interested in understanding the genetic basis for bacterial interactions with other organisms (be they plants, insects, fungi, other bacteria), and on how evolution shapes these interactions. By better understanding the rules and molecules that structure such relationships, we hope to develop new ways to manipulate these interactions (e.g. through the development of specific antimicrobial compounds) or shape their evolutionary dynamics through time.
Associate Research Scientist, Respiratory Sciences, Professor, BIO5 Institute, Professor, Cellular and Molecular Medicine, Professor, Physiological Sciences - GIDP, Professor, Physiology
Assistant Research Professor
Division Chief, Infectious Disease, Professor, BIO5 Institute, Professor, Immunobiology, Professor, Medicine
Dr. Connick is a physician scientist who has dedicated her career to the improvement of health of individuals living with or at risk for HIV-1 infection. Her research ranges from laboratory based investigations of HIV-1 immunopathogenesis to clinical and epidemiological studies of novel immunotherapies and other interventions to improve health outcomes in people living with HIV-1.
Associate Professor, BIO5 Institute, Associate Professor, Immunobiology, Associate Professor, Neurology, Associate Professor, Neuroscience - GIDP, Associate Professor, Neurosurgery, Associate Professor, Psychology, Research Scientist
Approximately 795,000 Americans suffer a stroke each year, and 400,000 will experience long-term disability. The number of stroke survivors in the population is expected to double by 2025. Currently, treatments for stroke patients are limited to tissue plasminogen activator (TPA), but its use is limited to the first few hours after stroke. Therefore, the goal of our research is to develop new therapeutics that can promote repair and recovery in this rapidly growing population.
Associate Professor, BIO5 Institute, Associate Professor, Basic Medical Sciences, Associate Professor, Clinical Translational Sciences, Associate Professor, Obstetrics and Gynecology
Professor, BIO5 Institute, Professor, Immunobiology, Professor, Medicine, Professor, Pathology, Professor, Pediatrics, Program Director, Blood and Bone Marrow Transplant, Professor, Cancer Biology - GIDP
Augmenting immune responses to cancer. Reducing relapse and graft versus host disease after hematopoietic cell transplantation.
Chair, Department of Medicine, Professor, BIO5 Institute, Professor, Medicine
Monica Kraft's research focus is in the areas of adult asthma, the role of infection in asthma and the role of the distal lung in asthma and airway remodeling.
Associate Professor, Immunobiology, Associate Professor, BIO5 Institute, Associate Professor, Genetics - GIDP
Michael Kuhns' research program is focused on (i) increasing our basic understanding of how T cell fate decisions are made (e.g. development, activation, differentiation, effector functions), and (ii) increasing their working knowledge of how to manipulate these decisions to direct T cells towards a desired outcome, such as increasing responses to vaccines or tumors, preventing transplant rejection, or attenuating autoimmunity.
Associate Professor, BIO5 Institute, Associate Professor, Cellular and Molecular Medicine, Associate Professor, Clinical Translational Sciences, Associate Professor, Immunobiology, Associate Professor, Medicine
Julie Ledford's research focuses on respiratory disease, and genetic and molecular mechanisms of allergic airway diseases in children.
Associate Professor, Cellular and Molecular Medicine, Associate Professor, BIO5 Institute, Associate Professor, Immunobiology
Director, Asthma / Airway Disease Research Center, Endowed Chair, Swift - McNear, Professor, BIO5 Institute, Professor, Pediatrics, Regents Professor, Professor, Genetics - GIDP
Co-Director, Arizona Center on Aging, Department Head, Immunobiology, Professor, BIO5 Institute, Professor, Immunobiology, Professor, Medicine, Professor, Nutritional Sciences, Professor, Genetics - GIDP, Professor, Neuroscience - GIDP
Professor, BIO5 Institute, Professor, Chemistry and Biochemistry, Professor, Chemistry and Biochemistry-Sci, Professor, Immunobiology
How we sense and react to our environment is communicated in the cell by vast networks of highly dynamic, interacting proteins. These interactions are regulated in both space and time, and it is this tight regulation that allows signals from outside of the cell to be rapidly and precisely transmitted to the nucleus leading to the appropriate, and healthy, cellular response. My research integrates structural biology, biophysics and biochemistry in order to understand how these signals and to develop novel drugs for the treatment of cancer, autoimmune disorders and antibiotic resistance. Lab website: https://sites.google.com/view/pagelaboratory
Professor, Aerospace-Mechanical Engineering, Professor, BIO5 Institute, Professor, Biomedical Engineering, Professor, Cellular and Molecular Medicine, Professor, Physiology, Professor, Surgery
Associate Professor, Applied BioSciences - GIDP, Associate Professor, BIO5 Institute, Associate Professor, Pathology - (Research Scholar Track)
We are studying how tumor cells escape immunosurveillance, a hallmark of cancer, in aggressive lymphomas. MHCII is a protein important for immunosurveillance. We are studying the underlying mechanisms of altered regulation of MHCII in lymphoma cells and its effects on tumor immunosurveillance.