Infectious diseases
Professor, Plant Science, Regents Professor, Plant Sciences, Research Associate Professor, Entomology, Professor, Entomology / Insect Science - GIDP, Professor, BIO5 Institute, Member of the General Faculty, Member of the Graduate Faculty
Unravel the phylodynamics and transmission-specific determinants of emerging plant virus/fastidious bacteria-insect vector complexes, and translate new knowledge to abate pathogen spread in food systems.
Professor, Medicine, Professor, Internal Medicine, Professor, Immunobiology, Director, Valley Fever Center for Excellence, Member of the Graduate Faculty, Professor, BIO5 Institute
Valley Fever (coccidioidomycosis) occurs more in Arizona than anywhere else. My research and others at the Valley Fever Center for Excellence involve understanding how disease is caused by infection, how the immune system stops or prevents illness, and how we can better diagnose, treat, or prevent this public health problem.
Associate Professor, Chemistry and Biochemistry-Sci, Member of the Graduate Faculty, Associate Professor, BIO5 Institute
We seek to develop tools and strategies to expedite the understanding and treatment of the dengue virus. These advances will be transferable to other areas of virology and biochemistry. Along these lines, we are engaged in three core synergistic projects to answer the following questions: (1) Do unnatural metabolites incorporated into DENV serve as reporters for host-pathogen interactions? (2) What are the host-pathogen interactions in DENV that are targetable for diagnosis or treatment? (3) Is there a chemical reaction between two small molecules that reports on the interaction between DENV and host proteins?
Associate Professor, Associate Professor, Immunobiology, Associate Professor, Evelyn F Mcknight Brain Institute, Associate Professor, Neuroscience - GIDP, Associate Professor, Medicine, Associate Professor, BIO5 Institute
We study how a common intracellular parasite, Toxoplasma gondii, persists in, and potentially changes, the mammalian brain. Understanding the Toxoplasma-brain interaction offers the opportunity to develop better therapies to treat toxoplasmosis as well as giving new insights into how to manipulate the brain immune response which has been implicated in many neurodegenerative diseases.
Distinguished Professor, Chemistry and Biochemistry, Professor, Chemistry and Biochemistry, Professor, Molecular and Cellular Biology, Professor, Entomology / Insect Science - GIDP, Professor, BIO5 Institute
Assistant Research Scientist
Dr. Powell is an Assistant Research Scientist in the Valley Fever Center for Excellence. His work focuses on the use of animal models to study the host response to both Coccidioides vaccination as well as infection. Dr Powell uses a variety of transgenic mouse models coupled with cellular immunology to dissect these host responses. His particular interest is in the initial recognition steps that allow some hosts to control infection where others do not.
Associate Research Professor, Animal and Comparative Biomedical Sciences, Research Scientist
Professor, Animal and Comparative Biomedical Sciences, Co-Director, Collaboratory for Anti-infectives & Therapeutics, Professor, Immunobiology, Professor, BIO5 Institute, Associate Director, Research, Member of the General Faculty, Member of the Graduate Faculty
Our research efforts focus on bacteria that cause serious healthcare-associated infections, and those associated with antibiotic use. This infections disproportiOur federally-funded research focuses on infection prevention. Specifically, we study diseases such as Clostridium difficile Infection that affect populations worldwide ("One-Health" issue). Our current efforts are aimed at translating bench-research findings to the bedside. We have recently been awarded two patents for a novel biologic agent invention aimed at preventing bacterial infections in humans as well as food animals.onately affect the elderly, and those with compromised immune systems. One overarching goal of our studies is to develop safe, cost-effective, non-antibiotic interventions to prevent and treat bacterial diarrheas.
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