Microbiology
Assistant Professor, BIO5 Institute, Assistant Professor, Earth Microbiome
Professor, BIO5 Institute, Professor, Plant Science, Research Associate Professor, Entomology, Professor, Entomology / Insect Science - GIDP
Unravel the phylodynamics and transmission-specific determinants of emerging plant virus/fastidious bacteria-insect vector complexes, and translate new knowledge to abate pathogen spread in food systems.
Associate Professor, BIO5 Institute, Associate Professor, Cancer Biology - GIDP, Associate Professor, Immunobiology, Associate Professor, Molecular and Cellular Biology
We aim to understand the mechanisms of HPV infection, the cellular responses to HPV infection, and how the interplay between host and virus influences the outcome
Assistant Professor, BIO5 Institute, Assistant Professor, Soil / Subsurface Microbial Ecology
We investigate the myriad of ways microbes living in the wild (soil, water and air) affect Earth processes and our health.
Assistant Professor, BIO5 Institute, Assistant Professor, Gastrointestinal Microbiology, Assistant Professor, Physiological Sciences - GIDP
Professor, BIO5 Institute, Professor, Genetics - GIDP, Professor, Immunobiology, Professor, Plant Sciences, Professor, Applied BioSciences - GIDP
Upon infection, viruses must transport their genomes into cells and produce progeny, often under a strict time deadline. We study how the viral proteins interact with with each other and with host cell proteins to efficiently accomplish these processes.
Director, Valley Fever Center for Excellence, Professor, BIO5 Institute, Professor, Medicine
Valley Fever (coccidioidomycosis) occurs more in Arizona than anywhere else. My research and others at the Valley Fever Center for Excellence involve understanding how disease is caused by infection, how the immune system stops or prevents illness, and how we can better diagnose, treat, or prevent this public health problem.
Director, Graduate Program in Immunobiology, Professor, BIO5 Institute, Professor, Cancer Biology - GIDP, Professor, Cellular and Molecular Medicine, Professor, Genetics - GIDP, Professor, Immunobiology, Professor, Molecular and Cellular Biology
Dr. Goodrum's long-standing research focus is to understand the molecular virus-host interactions important to human cytomegalovirus (CMV) latency and persistence in the host. Her recent work has defined the epidermal growth factor receptor (EGFR) as primary pathway targeted by these viral determinants to switch between latent and replicative states of infection. The goal of their research program is to define the mechanistic underpinnings of HCMV latency and lay the foundation for clinical interventions to control CMV disease in all settings.
Professor, BIO5 Institute, Professor, Environmental Science, Professor, Plant Sciences
Martha Hawes is well known for her work on root border cells. Her entire career has focused on changing this perception and now border cells are described in numerous botany textbooks. Dr. Hawes has been very creative in designing experiments to understand the basic biology of this unique cell type especially in light of how border cells fight plant disease. Considering that the root tip serves as one of the major sources of root exudates that can attract microbial pathogens, the fact that this exceptionally vulnerable region of the root is protected from infection by the border cells is a real paradigm shift, especially via the mechanism.
Associate Professor, BIO5 Institute, Associate Professor, Basic Medical Sciences, Associate Professor, Clinical Translational Sciences, Associate Professor, Obstetrics and Gynecology
Assistant Professor, Agricultural-Biosystems Engineering, Assistant Professor, BIO5 Institute, Assistant Professor, Genetics - GIDP, Assistant Professor, Statistics-GIDP, Clinical Instructor, Pharmacy Practice-Science
Our lab focuses on large-scale –omics datasets, high-throughput computing, and big data analytics. We leverage these technologies to answer questions related to the relationship between microbes, their hosts, and the environment. In particular, we focus on viral-host interactions and co-evolution given environmental factors (i) in aquatic systems and (ii) for phage treatment of diabetic foot ulcers.
Associate Professor, BIO5 Institute, Associate Professor, Chemistry and Biochemistry-Sci
We seek to develop tools and strategies to expedite the understanding and treatment of the dengue virus. These advances will be transferable to other areas of virology and biochemistry. Along these lines, we are engaged in three core synergistic projects to answer the following questions: (1) Do unnatural metabolites incorporated into DENV serve as reporters for host-pathogen interactions? (2) What are the host-pathogen interactions in DENV that are targetable for diagnosis or treatment? (3) Is there a chemical reaction between two small molecules that reports on the interaction between DENV and host proteins?
Assistant Professor, Immunobiology, Assistant Professor, BIO5 Institute
Metals such as calcium and iron are essential to living organisms. Some metals in excess, like copper, are detrimental to bacteria. My laboratory studies this phenomenon in Streptococcus pneumoniae to find novels method for killing pathogenic bacteria.
Chair, Applied BioSciences - GIDP, Chair, Arid Lands Resources Sciences - GIDP, Professor, Natural Resources and the Environment, Professor, BIO5 Institute, Professor, Plant Sciences
Director, National Science Foundation Water Environmental Technology Center, Professor, Agricultural-Biosystems Engineering, Professor, BIO5 Institute, Professor, Environmental Science-Ext, Professor, Public Health
Endowed Chair, Thomas R Brown - Biomedical Engineering, Professor, BIO5 Institute, Professor, Biomedical Engineering, Professor, Electrical and Computer Engineering
Our group develops rapid, inexpensive tools for the immediate discovery and identification of infectious diseases. It is critical for highly populated areas and resource-poor environments to have access to immediate therapeutics to save their populations and prevent the spread of these diseases.
Assistant Professor, Immunobiology, Research Fellow, BIO5 Institute
All viruses hijack host cell machinery to facilitate their replication. My lab investigates how the production of infectious viral progeny relies on host metabolism. Our overall goal is to guide the development of novel antiviral therapies using information regarding how viruses hijack host metabolism.
Associate Professor, Animal and Comparative Biomedical Sciences, Associate Professor, BIO5 Institute
Director, Microbial Pathogenesis Program, Professor, Animal and Comparative Biomedical Sciences, Professor, BIO5 Institute, Professor, Biochemistry/Molecular Biophysics, Professor, Genetics - GIDP, Professor, Immunobiology, Professor, Molecular and Cellular Biology
How do bacteria "talk" to the body? How does the body reply to the microbe? How does this conversation affect your health and well being?
Assistant Professor, Agricultural-Biosystems Engineering, Assistant Professor, Animal and Comparative Biomedical Sciences, Assistant Professor, BIO5 Institute, Assistant Professor, Ecosystem Genomics, Assistant Professor, Genetics - GIDP
We study the biodiversity, biogeography, evolutionary origins, and ecological roles of plant-associated microorganisms. We use a combination of traditional culture-based microbiology, functional assays, and next-generation 'omics tools to study microbial symbiont communities in diverse lineages of land plants at scales ranging from local to global. We are interested in characterizing the biotic and abiotic factors shaping the assembly of plant-associated fungal communities, how community structure and diversity impacts ecosystem function, and the evolutionary dynamics of fungal symbiont evolution in the context of closely related pathogens and saprotrophs.
Associate Professor, Animal and Comparative Biomedical Sciences, Associate Professor, BIO5 Institute
Ninety children die every hour due to diarrhea. My laboratory uses the latest technology to understand how bacteria cause diarrhea in children. In addition to providing clues for new ways to prevent disease, our research helps us understand how the body maintains good health.
Assistant Professor, Applied BioSciences - GIDP, Assistant Research Professor, Director, Viper Institute
Associate Director, Microbiome, Department Head, Ecology and Evolutionary Biology, Professor, BIO5 Institute, Professor, Ecology and Evolutionary Biology, Professor, Genetics - GIDP
Associate Professor, Plant Sciences, Associate Professor, BIO5 Institute