Natural sciences
Professor, Applied Mathematics - GIDP, Professor, BIO5 Institute, Professor, Chemistry and Biochemistry-Sci
Head, Pharmacology and Toxicology, Professor, BIO5 Institute, Professor, Pharmacology and Toxicology
Xinxin Ding, PhD, department head, Pharmacology and Toxicology, College of Pharmacy—studies enzyme function, regulation and genetics as applied to translational research for drug safety and efficacy and genetic and environmental risks for chemical toxicity. Author of nearly 200 peer-reviewed papers, book chapters and articles, he serves as associate editor for “Drug Metabolism and Disposition” and “Acta Pharmaeutica Sinica B.” Grants from the National Cancer Institute and National Institute of Environmental Health Sciences of the National Institute of Health fund his work, in part. Former chair of the NIH XNDA study section (2016-2018), he currently chairs (2018-19) Drug Metabolism and Disposition Division of the American Society for Pharmacology and Experimental Therapeutics..
Professor, BIO5 Institute, Professor, Chemistry and Biochemistry-Sci
The broad objective of our research program in Bioorganic Chemistry and Chemical Biology is to construct protein therapeutics, protein mimetics, biomaterials, and biosensors. Our research at the University of Arizona is highly multidisciplinary and utilizes techniques in organic synthesis, biochemistry, molecular biology, and a host of physical characterization methods. Our research motto is simple: Unraveling mysteries and Enabling discoveries.
Professor, BIO5 Institute, Professor, Biomedical Engineering, Professor, Cellular and Molecular Medicine, Professor, Genetics - GIDP, Professor, Molecular and Cellular Biology, Professor, Physiological Sciences - GIDP, Professor, Physiology
Our research is focused on elucidating the structure and function of titin and nebulin, two large filamentous proteins found in muscle. We use a range of model systems with a major focus on KO and TG mouse models. The techniques that we use range from single molecule mechanics, (immuno) electron microscopy, exon microarray analysis, in vitro motility assays, low angle X-ray diffraction, cell physiology (including calcium imaging), muscle mechanics, and isolated heart physiology.
Director, Natural Products Center, Professor, Arid Lands Resources Sciences - GIDP, Professor, BIO5 Institute, Professor, Cancer Biology - GIDP, Professor, Natural Resources and the Environment, Professor, Pharmacology and Toxicology
Discovery of natural products from plants and their associated microorganisms as potential drugs to treat cancer. Application of medicinal chemistry approach for structure-activity relationship studies and to obtain compounds for preclinical evaluation. Development of alternative agricultural systems for sustainable utilization of natural resources.
Professor, BIO5 Institute, Professor, Pharmacology and Toxicology
The Hulme group is focused on small molecule drug design and developing enabling chemical methodologies to expedite the drug discovery process. The development of small molecule inhibitors of kinases is of particular interest.
Assistant Professor, Astronomy, Assistant Professor, Genetics - GIDP, Assistant Professor, Lunar and Planetary Laboratory, Assistant Professor, Molecular and Cellular Biology, Assistant Professor, Planetary Sciences
Professor Betül Kaçar is an astrobiologist exploring the origins of life on Earth and finding life on other planets in the Universe. She is an Assistant Professor at the University of Arizona in the Departments of Molecular & Cellular Biology as well as Astronomy and the Lunar & Planetary Laboratories. Prior to Arizona, she was a NASA Astrobiology Postdoctoral Fellow at Harvard University where she developed molecular systems to bring ancient DNA sequences into the laboratory for physical, chemical and biological characterization. Her research is supported by NASA Exobiology and Evolutionary Biology Programs, NASA Astrobiology Program, the John Templeton Foundation, the National Science Foundation, Harvard University Origins Initiative as well as the University of Arizona Foundation. Betul is one of the Principal Investigators of the NASA Astrobiology Institute Reliving the Past node, is an associate member of the NASA Nexus for Exoplanet System Science designed to foster interdisciplinary collaboration in the search for life on exoplanets, and currently holds an Adjunct Professor position at Earth-Life Science Institute in Tokyo, Japan, which is dedicated to understanding the origins of life. She was named a Scialog Fellow of the Heising-Simons Foundation and Kavli Foundation to study the Biosignatures and Life in the Universe in 2020, a NASA Early Career Fellow in 2019, and a Way Cool Scientist by the Science Club for Girls in 2017. Her research has gained national and international attention, and has been featured by CNN, BBC, NOVA Science, Discover Magazine, NPR Science Friday and Scientific American.
Assistant Professor, BIO5 Institute, Assistant Professor, Biomedical Engineering, Assistant Professor, Optical Sciences
We are developing low-cost in vivo microscopy devices that can visualize cellular details of human tissues in vivo and help disease diagnosis and treatment in low-resource settings, high-speed tissue microscopy technologies that can examine entire organ under risk of having malignant diseases and detect small, early-stage lesions, and miniature microscopy devices that have the potential to examine anatomically-challenging human organs and facilitate integration of microscopic imaging with other imaging modalities.
Assistant Professor, BIO5 Institute, Assistant Professor, Biomedical / Materials Science Engineer, Assistant Professor, Biomedical Engineering
Minkyu Kim's research interests are in the areas of biopolymers and biomaterials for advanced national defense and healthcare. He is currently working to develop functional biopolymer materials for the treatment of antimicrobial-resistance diseases and atherosclerosis.
Professor, Applied Mathematics - GIDP, Professor, BIO5 Institute, Professor, Optical Sciences, Professor, Radiology
Matthew Kupinski works in diverse areas of imaging including x-ray, gamma-ray, diffuse optical, magnetic resonance, and neutron imaging.
Assistant Professor, BIO5 Institute, Assistant Professor, Chemistry and Biochemistry - Med, Assistant Professor, Chemistry and Biochemistry-Sci
The Marty Lab uses mass spectrometry to study interactions of membrane proteins, peptides, and lipids within nanoscale membrane mimetics.
Professor, BIO5 Institute, Professor, Chemistry and Biochemistry-Sci
Professor, BIO5 Institute, Regents Professor, Professor, Chemistry and Biochemistry-Sci
Professor, BIO5 Institute, Professor, Chemistry and Biochemistry-Sci
Associate, Center for Toxicology, Professor, Animal and Comparative Biomedical Sciences, Professor, BIO5 Institute, Professor, Nutritional Sciences, Professor, Cancer Biology - GIDP
Professor, Applied Mathematics - GIDP, Professor, BIO5 Institute, Regents Professor
Distinguished Scholar, Chemical and Environmental Engineering, Professor, Chemical and Environmental Engineering, Professor, Global Change - GIDP, Professor, Hydrology / Atmospheric Sciences, Professor, Optical Sciences, Professor, Public Health, da Vinci Fellow
Armin's research focuses on the effect of aerosol particles on the environment, clouds and rainfall, climate, and public health/welfare. A suite of synergistic methods are used for this research, including laboratory experiments, ground and airborne field measurements, modeling, and remote sensing observations. Since 2004, he has participated in 15 airborne field projects, including six as a mission PI with the CIRPAS Twin Otter (sponsored by ONR). Currently, Armin is involved with a multi-year NASA project called CAMP2EX (Cloud and Aerosol Monsoonal Processes-Philippines Experiment; and is serving as the PI of a NASA Earth Venture Suborbital-3 (EVS-3) mission called ACTIVATE (Aerosol Cloud meTeorology Interactions oVer the western ATlantic Experiment;
Director, Ligand Discovery Laboratory, Research Associate Professor, Pharmacology, Research Professor
Co-Director, Arizona Center for Drug Discovery, Professor, Chemistry and Biochemistry, Professor, Pharmacology and Toxicology