Neurophysiology
Distinguished Professor, Professor, BIO5 Institute, Professor, Cognitive Science - GIDP, Professor, Psychology, Professor, Neuroscience - GIDP
Depression is a major health problem that is often chronic or recurrent. Existing treatments have limited effectiveness, and are provided wihtout a clear indication that they will match a particular patient's needs. In this era of precision medicine, we strive to develop neurally-informed treatments for depression and related disorders.
Assistant Professor, BIO5 Institute, Assistant Professor, Cognitive Science - GIDP, Assistant Professor, Evelyn F Mcknight Brain Institute, Assistant Professor, Psychology
Associate Professor, BIO5 Institute, Associate Professor, Biomedical Engineering, Associate Professor, Neuroscience - GIDP, Associate Professor, Physiological Sciences - GIDP, Associate Professor, Physiology
My laboratory studies how the retina takes visual information about the world and transmits it to the brain. We are trying to understand how this signaling responds to changing amounts of background light and becomes dysfunctional in diabetes.
Associate Professor, Applied Mathematics - GIDP, Associate Professor, BIO5 Institute, Associate Professor, Electrical and Computer Engineering, Associate Professor, Entomology / Insect Science - GIDP, Associate Professor, Neuroscience, Associate Professor, Neuroscience - GIDP
Professor, Anesthesiology, Professor, BIO5 Institute, Professor, Neuroscience - GIDP, Professor, Pharmacology
The focus of my laboratory’s’ research is to understand how ion channels, specifically, voltage-gated calcium and sodium channels, are regulated by novel protein interactions. Recent studies in my laboratory have focused on targeting protein-protein interactions with biologics (peptide aptamers) and small molecules; testing the activity of these novel chemical entities in biochemical and immunofluorescent-based assays of trafficking; examining their protein interaction signatures; testing them with whole cell voltage-clamp electrophysiology and voltage- and calcium sensitive fluorescence-based imaging. Regulating these protein networks to modulate the activity of ion channels in neurodegenerative diseases (Chronic Pain, Migraine, and Neurofibromatosis) is a key focus of the laboratory.
Assistant Professor, BIO5 Institute, Assistant Professor, Cognitive Science - GIDP, Assistant Professor, Speech/Language and Hearing
My research examines neural factors which affect language functions, and how these change across life-span and are influenced by stroke, brain injury and neurodegenerative disorders. In my work, I use combination of cognitive measures and multimodal neuroimaging techniques (fMRI, EEG/ERPs, MEG). I am also interested in recovery of function, and treatment approaches involving speech-language therapy in combination with noninvasive brain stimulation techniques.
Assistant Professor, Assistant Professor, BIO5 Institute, Assistant Professor, Neurology, Assistant Professor, Neuroscience - GIDP, Assistant Professor, Speech and Hearing Science
Associate Professor, Applied Mathematics - GIDP, Associate Professor, BIO5 Institute, Associate Professor, Biomedical Engineering, Associate Professor, Neuroscience - GIDP, Associate Professor, Optical Sciences, Professor, Medical Imaging
We develop cutting-edge imaging technology, integrating light, ultrasound and electricity, to diagnose and treat diseases ranging from epilepsy to breast cancer. Novel sources for ultrasound contrast include optical and microwave absorption, mechanical strain, and electrical current. We visualize electrical brain “stormsˮ during uncontrollable seizures and envision “smartˮ photoacoustic agents that seek-and-destroy deadly tumors.