Associate Dean, Research-Agriculture and Life Sciences, Associate Vice President for Research, Agriculture - Life and Veterinary Sciences / Cooperative Extension, Professor, BIO5 Institute, Professor, Cellular and Molecular Medicine, Professor, Molecular and Cellular Biology
Assistant Professor, BIO5 Institute, Assistant Professor, Neuroscience, Assistant Professor, Neuroscience - GIDP
We study how neuronal axons and their terminals respond to stress and damage, and how the molecules activated by stress and damage execute decisions about whether to repair themselves or self-destruct. We hope to identify target molecules that could be used to prevent axon and nerve terminal loss in diseases ranging from diabetic neuropathy to Alzheimer's disease.
Assistant Professor, BIO5 Institute, Assistant Professor, Chemistry and Biochemistry - Med, Associate Professor
Associate Professor, BIO5 Institute, Associate Professor, Chemistry and Biochemistry-Sci
Professor, BIO5 Institute, Professor, Cancer Biology - GIDP, Professor, Cellular and Molecular Medicine, Professor, Genetics - GIDP
I am investigating a human connective tissue disorder in mice. I am also investigating the role of gut bacteria in colon cancer risk in both a mouse model of colon cancer and in humans with colon cancer.
Assistant Professor, BIO5 Institute, Assistant Professor, Chemistry and Biochemistry
Andrew Hausrath's lab studies the structures of proteins and complexes using X-ray crystallography, microscopy, and biophysical techniques. Proteins of certain classes are heavily represented as components of complexes. Knowledge of the structures and properties of the proteins which function within higher-order complexes then stimulates development of improved models and theory about how such complexes carry out their functions in the cell. Systems of current interest include the ATP synthase, the signaling hormone adiponectin, and the higher-order organization of chromatin in the nucleus.
Associate Director, Shared Resources, Associate Professor, Pharmacology, Director, Aribi Institute, Professor, BIO5 Institute, Professor, Biomedical Engineering, Professor, Physiological Sciences - GIDP, Professor, Physiology
Precise diagnosis and treatment of disease requires an ability to target agents to specific tissues and cell types within those tissues. We are developing agents that exhibit cell type specificity for these purposes.
Professor, BIO5 Institute, Professor, Chemistry and Biochemistry, Professor, Chemistry and Biochemistry-Sci, Professor, Immunobiology
How we sense and react to our environment is communicated in the cell by vast networks of highly dynamic, interacting proteins. These interactions are regulated in both space and time, and it is this tight regulation that allows signals from outside of the cell to be rapidly and precisely transmitted to the nucleus leading to the appropriate, and healthy, cellular response. My research integrates structural biology, biophysics and biochemistry in order to understand how these signals and to develop novel drugs for the treatment of cancer, autoimmune disorders and antibiotic resistance.