Dominic V Mcgrath
Publications
PMID: 16853639;Abstract:
Four generations of monodendrons with multiple dodecyl alkyl tails (AA-N, N representing number of alkyl tails from 1 to 8), an azobenzene spacer group, and a carboxylic acid polar head have been studied at the air-water and air-solid interface using AFM, GIXD, X-ray reflectivity, and UV - vis spectrometry. The one and two tail molecules formed orthorhombic lateral packing with long-range intramonolayer ordering. Good agreement between molecular models and thickness measurements indicated that the one and two tail molecules orient along the surface normal. The increase in the cross-sectional mismatch caused by the presence of the multiple chains for the higher generations disrupted the long-range ordering and forced the alkyl tails to adopt quasi-hexagonal structure. The higher generations (AA-4 and AA-8) formed a kinked structure with the alkyl tails oriented perpendicular to the surface with the azobenzene group tilted at a large degree toward the surface. The photoisomerization behavior in dilute solutions, at the air-water interface, and for grafted layers demonstrated that lower generation monodendrons maintained the photochromic behavior after chemical grafting to the silicon substrates, although the confinement of the molecules in monolayers significantly increased the reorganization time. © 2005 American Chemical Society.
PMID: 20925328;Abstract:
The convergent synthesis of geometrically degradable dendrimers based on the 2,4-bis(hydroxymethyl)phenol subunit is presented. The key step of the synthetic scheme involves the CuI/3,4,7,8-tetramethyl-1,10-phenanthroline- catalyzed coupling of aryl iodides and alcohols. The synthesis and disassembly of these compounds is discussed. © 2010 American Chemical Society.
Abstract:
Zeroth through third generations of amphiphilic monodendrons containing a benzyl-15-crown-5 polar focal point, photochromic spacer, and alkyl tails as peripheral groups have been investigated for their ability to form photoresponsive surface monolayers. Thickness measurements, scanning probe microscopy, and molecular modeling were used to determine the microstructure of the monolayers. The tilted molecular packing of dendrons in the monolayers is proposed with bulky dendritic shell prohibiting dense packing of azobenzene groups and the aggregate formation. The two-stage trans-cis isomerization was observed for the photochromic monodendron layers composed of various generation dendrons. Fast changes within the first several minutes occurred in the azobenzene-containing monodendrons until the conversion of trans-cis isomerization reaches 13-33%. Then lateral steric hindrances in the monolayer decreases the transformation rate by three orders of magnitude. Diffusion limited intralayer reorganization is suggested to be a limiting factor in the rate of photoisomerization changes. © 2002 Elsevier Science B.V. All rights reserved.