Scott B Going

Scott B Going

Director, School of Nutritional Sciences and Wellness
Professor, Nutritional Sciences
Professor, Public Health
Professor, Physiology
Professor, Physiological Sciences - GIDP
Professor, BIO5 Institute
Primary Department
Department Affiliations
Contact
(520) 626-3432

Work Summary

Scott Going is an expert in models and methods for assessment of changes in body composition during growth, and with aging, and is currently investigating the effects of chronic exercise versus hormone replacement therapy on bone, soft tissue composition and muscle strength in postmenopausal women, as well as the role of exercise in obesity prevention in children.

Research Interest

Current projects include:The Bone, Estrogen and Strength Training (BEST) study, a randomized prospective study of the effects of hormone replacement therapy on bone mineral density, soft tissue composition, and muscle strength in postmenopausal women (National Institutes of Health). The Profile-based Internet-linked Obesity Treatment study (PILOT), a randomized study of internet support for weight maintenance after weight loss in peri-menopausal women (National Institutes of Health). The Trial of Activity for Adolescent Girls (TAAG) study, a multi-center, school-based activity trial designed to prevent the usual decline in physical activity in adolescent girls (National Institutes of Health). The Adequate Calcium Today (ACT) study, a randomized multi-center study of a behavioral intervention to promote healthy eating, calcium intake and bone development in adolescent girls (United States Department of Agriculture). The Healthy Weight in Adolescents study, a randomized, multi-center study of the effects of a science-based curriculum focused on concepts of energy balance on body weight and composition in adolescent boys and girls (United States Department of Agriculture). The KNEE study, a randomized clinical trial of the effects of resistance exercise on disease progression, pain, and functional capacity in osteoarthritis patients (National Institutes of Health). The STRONG study, a randomized clinical trial of the effects of resistance exercise and Remicaid on disease progression, pain, muscle strength and functional capacity in rheumatoid arthritis patients (Centocor, Inc.). Partners for Healthy Active Children, Campañeros Para Niños Sano y Actives, designed to create and implement research-based physical education and nutrition curricula at YMCA after-school programs and Sunnyside District elementary schools, in alignment with the State o Arizona , Health and Physical Activity standards (Carol M. White Physical Education Program CFDA #84.215F). Longitudinal Changes in Hip Geometry, an observational and experimental cohort study of changes in muscle mass, hip structural parameters and hip bone strength in middle-aged and older women in the Women's Healthy Initiative study (National Institutes of Health).

Publications

Raves, D. M., Thomson, C. A., Roe, D., Funk, J. L., Jacobs, E. T., Blew, R., Lee, V. R., Jouflas, A. C., & Going, S. B. (2016). Diet quality is associated with lower total and visceral adiposity in Hispanics and non-Hispanic adolescent girls. The Journal of Nutrition.
Farr, J., Going, S. B., & Laddu, D. (2014). Exercise, Hormones and Skeletal Adaptations during childhood and adolescence. Pediatric Exercise Science, 26, 384-391.
Bea, J. W., Woo, J., Hsu, C. C., Going, S. B., Horn, P., & Morrison, J. (2017). Adolescent Obesity and the Development of Cardiometabolic Disease in Black and White Girls at Age 19: The National Heart Lung and Blood Institute Growth and Health Study. Pediatrics.
Laddu, D. R., Farr, J. N., Lee, V. R., Blew, R. M., Lohman, T. G., & Going, S. B. (2014). Muscle density predicts changes in bone density and strength: a prospective pQCT study in girls.. Journal of Musculoskeletal and Neuronal Interactions, 14(2), 195-204.
Sardinha, L. B., Lohman, T. G., Teixeira, P. J., Guedes, D. P., & Going, S. B. (1998). Comparison of air displacement plethysmography with dual-energy X-ray absorptiometry and 3 field methods for estimating body composition in middle-aged men. The American journal of clinical nutrition, 68(4).

This study was designed to compare air displacement plethysmography with dual-energy X-ray absorptiometry (DXA) and 3 other field methods for estimation of body composition. Subjects were 62 healthy, white men aged 37.6+/-2.9 y (weight: 81.8+/-11.3 kg; height: 171.5+/-4.9 cm). Body composition was also assessed by using body mass index, single-frequency bioelectrical impedance analysis, multi-frequency bioelectrical impedance spectroscopy, and the skinfold-thickness equations of Jackson and Pollock and Durnin and Womersley. Percentage body fat (%BF) with the plethysmograph was 23.4+/-7.0 and with DXA was 26.0+/-7.4. The 2.6% mean difference was significant (P 0.05). Total error was 3.7%BF. As assessed by multiple regression analysis, %BF with the plethysmograph, age, weight, and height yielded a DXA-adjusted R2 value of 89.5% fat and an SEE of 2.4% fat. All other models had higher SEEs and lower adjusted R2 values: 4.3% and 66.5% for body mass index, 3.3% and 79.8% for bioelectrical impedance analysis, 3.6% and 76.2% for bioelectrical impedance spectroscopy, 3.7% and 74.55% for the equations of Jackson and Pollock, and 3.9% and 71.6% for the equations of Durnin and Womersley, respectively. The plethysmograph also predicted fat mass and fat-free mass more accurately than all other models, with a lower SEE and higher adjusted R2 value. In conclusion, although %BF was systematically underestimated, body composition was closely estimated with air displacement plethysmography in middle-aged men.