Valley Fever Center for Excellence

Daniel Powell

Assistant Research Scientist
Department Affiliations
Contact
(520) 626-6447

Work Summary

Dr. Powell is an Assistant Research Scientist in the Valley Fever Center for Excellence. His work focuses on the use of animal models to study the host response to both Coccidioides vaccination as well as infection. Dr Powell uses a variety of transgenic mouse models coupled with cellular immunology to dissect these host responses. His particular interest is in the initial recognition steps that allow some hosts to control infection where others do not.

Research Interest

My approach to infectious diseases has always been multi-disciplinary. There is a constant arms race between both host and pathogen. Infection changes the host response and the host response exerts changes on the pathogen. Approaching these problems from a single host or pathogen centric view limits the chance for complete understanding. Most of my published works have been in the interface between both the host and the pathogen. Joining Bio5 will allow me to join other scientist interested in multi-disciplinary answers to complex questions.

Lisa Shubitz

Associate Research Professor, Animal and Comparative Biomedical Sciences
Research Scientist
Department Affiliations
Contact
520-626-8198

Research Interest

Dr. Shubitz has been engaged with valley fever research with the Valley Fever Center for Excellence for 25 years under the direction of Dr. John Galgiani. Her research focuses on murine models of coccidioidomycosis. The bulk of her research has focused on vaccine development and in collaboration with Dr. Marc Orbach has developed a live, avirulent vaccine to prevent valley fever in dogs. The vaccine is being developed commercially. Her other interests and studies include testing new antifungal drugs in mice, immunology and immunogenetics of resistance in mice, and why dogs develop severe disease more often than humans. She is interested in developing studies of the genetics of susceptibility in dogs with other collaborators. Dr. Shubitz also consults on valley fever in companion animals. She is heavily focused on bringing research from the lab to improve clinical care, and using clinical observations to drive research to improve treatment and care of valley fever in humans and animals. The dog vaccine is a stepping stone to development of the vaccine to prevent valley fever in people.