Biology
Professor, BIO5 Institute, Professor, Immunobiology
Professor, BIO5 Institute, Professor, Evelyn F Mcknight Brain Institute, Professor, Neuroscience - GIDP, Professor, Physiological Sciences - GIDP, Professor, Psychiatry, Professor, Psychology
My research focuses on advancing our understanding of how and why aging impacts the brain and associated cognitive abilities. I use neuroimaging scans of brain function and structure together with measures of cognition and health status to identify those factors that influence brain aging and the risk for Alzheimer's disease. My work also includes identifying how health and lifestyle interventions can help to delay or prevent the effects of brain aging and Alzheimer's disease.
Associate Professor, Agricultural-Biosystems Engineering, Associate Professor, BIO5 Institute, Associate Professor, Public Health, Associate Professor, Statistics-GIDP
Associate Dean, Research-Agriculture and Life Sciences, Associate Vice President for Research, Agriculture - Life and Veterinary Sciences / Cooperative Extension, Professor, BIO5 Institute, Professor, Cellular and Molecular Medicine, Professor, Molecular and Cellular Biology
Professor, BIO5 Institute, Professor, Ecology and Evolutionary Biology
Professor, BIO5 Institute, Professor, Evelyn F Mcknight Brain Institute, Professor, Physiology, Professor, Speech/Language and Hearing
Associate Professor, Medicine - (Research Scholar Track), Coordinator, Phase I/II Clinical Trials, Research Assistant Professor, BIO5 Institute, Associate Professor, Pharmacy Practice-Science
Assistant Professor, BIO5 Institute, Assistant Professor, Earth Microbiome
Associate Professor, Associate Professor, BIO5 Institute
Associate Professor, American Indian Studies-GIDP, Associate Professor, BIO5 Institute, Associate Professor, Chemical and Environmental Engineering, Associate Professor, Public Health
Associate Professor, Entomology / Insect Science - GIDP, Associate Research Professor, Associate Research Scientist, BIO5 Institute, Associate Research Scientist, Biosphere 2
Adjunct Associate Professor, Animal and Comparative Biomedical Sciences, Associate Research Scientist, BIO5 Institute, Director/Attending Veterinarian, University Animal Care, Veterinary Specialist
Associate Professor, BIO5 Institute, Associate Professor, Genetics - GIDP, Associate Professor, Immunobiology, Associate Professor, Surgery
Assistant Professor, BIO5 Institute, Assistant Professor, Neuroscience, Assistant Professor, Neuroscience - GIDP
We study how neuronal axons and their terminals respond to stress and damage, and how the molecules activated by stress and damage execute decisions about whether to repair themselves or self-destruct. We hope to identify target molecules that could be used to prevent axon and nerve terminal loss in diseases ranging from diabetic neuropathy to Alzheimer's disease.
Professor, BIO5 Institute, Professor, Mathematics, Professor, Statistics-GIDP
Associate Research Scientist, Respiratory Sciences, Professor, BIO5 Institute, Professor, Cellular and Molecular Medicine, Professor, Physiological Sciences - GIDP, Professor, Physiology
Medical Director, Viper Institute
Professor, BIO5 Institute, Professor, Ecology and Evolutionary Biology, Professor, Entomology / Insect Science - GIDP, University Distinguished Professor
Professor, BIO5 Institute, Professor, Plant Science, Research Associate Professor, Entomology, Professor, Entomology / Insect Science - GIDP
Unravel the phylodynamics and transmission-specific determinants of emerging plant virus/fastidious bacteria-insect vector complexes, and translate new knowledge to abate pathogen spread in food systems.
Professor, Applied Mathematics - GIDP, Professor, BIO5 Institute, Professor, Chemistry and Biochemistry-Sci
Assistant Professor, BIO5 Institute, Assistant Professor, Molecular and Cellular Biology
Adjunct Professor, Mining and Geological Engineering, Associate Dean, Research-Public Health, Professor, BIO5 Institute, Professor, Public Health, Associate Dean, Research - Mel and Enid Zuckerman College of Public Health
Research Professor, Research Professor, BIO5 Institute
Peptides and proteins play a vital role in almost every cellular process in living organisms. Our research discovers and determines structural information on peptides and proteins to design drugs to more effectively treat human disease.
Associate Professor, BIO5 Institute, Associate Professor, Cancer Biology - GIDP, Associate Professor, Immunobiology, Associate Professor, Molecular and Cellular Biology
We aim to understand the mechanisms of HPV infection, the cellular responses to HPV infection, and how the interplay between host and virus influences the outcome
Associate Professor, Genetics - GIDP, Associate Professor, Molecular and Cellular Biology, Associate Professor, BIO5 Institute
Assistant Professor, BIO5 Institute, Assistant Professor, Soil / Subsurface Microbial Ecology
We investigate the myriad of ways microbes living in the wild (soil, water and air) affect Earth processes and our health.
Professor, BIO5 Institute, Professor, Entomology, Professor, Entomology / Insect Science - GIDP
Assistant Professor, BIO5 Institute, Assistant Professor, Chemistry and Biochemistry - Med, Associate Professor
Associate, Center for Toxicology, Professor, Pharmacology, Professor, Pharmacology and Toxicology, Professor, Applied BioSciences - GIDP, Professor, Cancer Biology - GIDP
Associate Professor, BIO5 Institute, Associate Professor, Chemistry and Biochemistry-Sci
Professor, Agricultural-Biosystems Engineering, Professor, Arid Lands Resources Sciences - GIDP, Professor, BIO5 Institute
Associate Professor, BIO5 Institute, Professor, Environmental Science-Ext
Professor, BIO5 Institute, Professor, Cancer Biology - GIDP, Professor, Cellular and Molecular Medicine, Professor, Genetics - GIDP
I am investigating a human connective tissue disorder in mice. I am also investigating the role of gut bacteria in colon cancer risk in both a mouse model of colon cancer and in humans with colon cancer.
Professor, BIO5 Institute, Professor, Cognitive Science - GIDP, Professor, Ecology and Evolutionary Biology, Professor, Entomology / Insect Science - GIDP, Professor, Neuroscience - GIDP, Professor, Psychology, Professor, Neuroscience
Assistant Professor, BIO5 Institute, Assistant Professor, Gastrointestinal Microbiology, Assistant Professor, Physiological Sciences - GIDP
Associate Professor, BIO5 Institute, Associate Professor, Ecology and Evolutionary Biology
Associate Professor, BIO5 Institute, Associate Professor, Biomedical Engineering, Associate Professor, Neuroscience - GIDP, Associate Professor, Physiological Sciences - GIDP, Associate Professor, Physiology
My laboratory studies how the retina takes visual information about the world and transmits it to the brain. We are trying to understand how this signaling responds to changing amounts of background light and becomes dysfunctional in diabetes.
Professor, BIO5 Institute, Professor, Genetics - GIDP, Professor, Immunobiology, Professor, Plant Sciences, Professor, Applied BioSciences - GIDP
Upon infection, viruses must transport their genomes into cells and produce progeny, often under a strict time deadline. We study how the viral proteins interact with with each other and with host cell proteins to efficiently accomplish these processes.
Assistant Professor, BIO5 Institute, Assistant Professor, Evelyn F Mcknight Brain Institute, Assistant Professor, Neurology, Assistant Professor, Neuroscience - GIDP, Assistant Professor, Psychology
Fabian Fernandez's work includes a focus on identifying circadian factors during middle age that increase risk for later-life cognitive impairment, developing novel, light-based treatments to stem loss of cognition during aging, and establishing basic principles for how circadian function shapes memory processing.
Assistant Research Scientist, Cancer Center Division, Associate Professor, BIO5 Institute, Investigator, Center for Toxicology, Professor, Pharmacology and Toxicology, Professor, Cancer Biology - GIDP
Bernard Futscher's lab is studying the molecular origins of human cancer. Understanding epigenetic dysfunction in human cancer has been Dr. Futscher's primary research focus since establishing his own independent laboratory. This epigenetic research has moved into the area of noncoding RNAs and their potential role in cancer cell immortality.
Professor, BIO5 Institute, Professor, Biomedical Engineering, Professor, Plant Science
I examine the molecular functions of the different cells found in the tissues and organs of plants and animals and how they combine these functions to optimize the health and vigor of the organism.
Assistant Professor, Pharmacology and Toxicology
Research Professor, Center for Toxicology, Research Professor, BIO5 Institute
Dr. Gandolfi directed toxicology research projects at the University of Arizona since 1978. His research interests are in the toxicity of halogenated hydrocarbons and metals with an emphasis on hepatic and renal systems. He was also active in developing in vitro toxicity models and the disposition of xenobiotics.
Professor, BIO5 Institute, Professor, Internal Medicine, Professor, Medicine, Professor, Pharmacology and Toxicology, Professor, Physiological Sciences - GIDP, Professor, Physiology
The Garcia laboratory works to understand the molecular mechanisms of lung inflammatory processes, particularly those producing lung edema or vascular leak. The laboratory focus is to investigate gene discovery, protein function assessment, SNP discovery, genetic manipulation, in vivo testing, and candidate gene and biomarker identification, working to translate basic research into potential novel clinical therapies.
Professor, BIO5 Institute, Professor, Chemistry and Biochemistry-Sci
The broad objective of our research program in Bioorganic Chemistry and Chemical Biology is to construct protein therapeutics, protein mimetics, biomaterials, and biosensors. Our research at the University of Arizona is highly multidisciplinary and utilizes techniques in organic synthesis, biochemistry, molecular biology, and a host of physical characterization methods. Our research motto is simple: Unraveling mysteries and Enabling discoveries.
Professor, BIO5 Institute, Professor, Medicine - (Research Scholar Track), Research Scientist
Our lab has a new treatment for heart failure. We have a biodegradable graft seeded with adult human cells that we put on the surface of the heart. The potential is to regenerate new heart muscle
Specialist, Entomology, Professor, BIO5 Institute, Professor, Entomology, Professor, Entomology / Insect Science - GIDP
Study the ecology of bed bugs and key vector mosquito species in order to improve management strategies.
Associate Professor, Animal and Comparative Biomedical Sciences, Associate Professor, BIO5 Institute
Professor, BIO5 Institute, Professor, Biomedical Engineering, Professor, Cellular and Molecular Medicine, Professor, Molecular and Cellular Biology, Professor, Physiological Sciences - GIDP, Professor, Physiology
Our research is focused on elucidating the structure and function of titin and nebulin, two large filamentous proteins found in muscle. We use a range of model systems with a major focus on KO and TG mouse models. The techniques that we use range from single molecule mechanics, (immuno) electron microscopy, exon microarray analysis, in vitro motility assays, low angle X-ray diffraction, cell physiology (including calcium imaging), muscle mechanics, and isolated heart physiology.
Co-Director, Sarver Heart Center, Department Head, Cellular and Molecular Medicine, Director, Molecular Cardiovascular Research Program, Professor, BIO5 Institute, Professor, Cellular and Molecular Medicine, Professor, Molecular and Cellular Biology, Vice Dean, Innovation and Development
The research in my laboratory is focused on identifying the components and molecular mechanisms regulating actin architecture in cardiac and skeletal muscle during normal development and disease. Control of actin filament lengths and dynamics is important for cell motility and architecture and is regulated in part by capping proteins that block elongation and depolymerization at both the fast-growing (barbed) and slow-growing (pointed) ends of the filaments.
Director, Epidemiology, Professor, BIO5 Institute, Professor, Medicine - (Tenure Track), Professor, Public Health, Research Scientist, Respiratory Sciences
Stefano Guerra's work includes an epidemiologic study, which used a household-based approach to assess prevalence and longitudinal changes in respiratory health. Other biomarker projects include a study on molecular biomarkers of asthma and COPD from the European Community Respiratory Health Survey.
Director, Natural Products Center, Professor, Arid Lands Resources Sciences - GIDP, Professor, BIO5 Institute, Professor, Cancer Biology - GIDP, Professor, Natural Resources and the Environment, Professor, Pharmacology and Toxicology
Discovery of natural products from plants and their associated microorganisms as potential drugs to treat cancer. Application of medicinal chemistry approach for structure-activity relationship studies and to obtain compounds for preclinical evaluation. Development of alternative agricultural systems for sustainable utilization of natural resources.
Associate Department Head, Molecular and Cellular Biology, Associate Professor, Applied BioSciences - GIDP, Associate Professor, Applied Mathematics - GIDP, Associate Professor, BIO5 Institute, Associate Professor, Ecology and Evolutionary Biology, Associate Professor, Genetics - GIDP, Associate Professor, Molecular and Cellular Biology, Associate Professor, Public Health, Associate Professor, Statistics-GIDP, Director, Graduate Studies
We learn history from the genomes of humans, tumors, and other species. Our studies reveal how evolution works at the molecular level, offering fundamental insight into how humans and pathogens adapt to challenges.
Associate Department Head, Ecology and Evolutionary Biology, Associate Professor, BIO5 Institute, Associate Professor, Ecology and Evolutionary Biology, Associate Professor, Genetics - GIDP
Jeremiah Hackett’s research interests are in the areas of genome evolution, the evolution of photosynthesis and the physiology of harmful algae. Part of his research investigates how eukaryotes acquire plastids through endosymbiosis and how this process influences genome evolution through gene transfer. Another main area of research is the ecology and physiology of harmful algae. His lab is using microarrays to determine global gene expression patterns of harmful algae under various growth conditions. These gene expression profiles will be used to determine the factors that lead to harmful algal blooms in the oceans.
Associate Director, Omics, Research Scientist, Arizona Research Labs, Research Scientist, BIO5 Institute, Research Scientist, Ecology and Evolutionary Biology, Research Scientist, Neurology

Michael Hammer has headed a productive research lab in human evolutionary genetics. His lab were early adopters of next generation sequencing (NGS) technology successfully employed NGS methods to identify molecular lesions causing neurodevelopmental disorders in undiagnosed children. His lab is also currently pursuing studies to identify modifier genes that alter the expression of major genes and how they contribute to phenotypic heterogeneity in Mendelian disorders.

Executive Director, AHSC Biorepository, Professor, BIO5 Institute, Professor, Immunobiology, Professor, Medicine, Professor, Applied BioSciences - GIDP
We are involved in banking clinical specimens obtained from various patients for use in biomarker discovery and clinical therapies. Clinical therapies may include regenerative medicine, transplant or gene therapy.
Associate Professor, BIO5 Institute, Associate Professor, Physiological Sciences - GIDP, Co-Chair, ABBS Program, Professor, Cellular and Molecular Medicine
The long-term goal of research in my lab is to understand the molecular mechanisms of muscle contraction. I am especially interested in how contractile proteins of muscle sarcomeres regulate the force and speed of contraction in the heart. The question is important from both basic science and clinical perspectives because mutations in sarcomere proteins of muscle are a leading cause of hypertrophic cardiomyopathy (HCM), the most common cause of sudden cardiac death in the young and a prevalent cause of heart failure in adults. Myosin binding protein-C (MyBP-C) is a muscle regulatory protein that speeds actomyosin cycling kinetics in response to adrenaline (b-adrenergic stimuli) and is one of the two most commonly affected proteins linked to HCM. Currently, the major research focus in my lab is understanding the mechanisms by which cMyBP-C regulates contractile speed and mechanisms by which mutations in cMyBP-C cause disease.
Assistant Professor, BIO5 Institute, Assistant Professor, Chemistry and Biochemistry
Andrew Hausrath's lab studies the structures of proteins and complexes using X-ray crystallography, microscopy, and biophysical techniques. Proteins of certain classes are heavily represented as components of complexes. Knowledge of the structures and properties of the proteins which function within higher-order complexes then stimulates development of improved models and theory about how such complexes carry out their functions in the cell. Systems of current interest include the ATP synthase, the signaling hormone adiponectin, and the higher-order organization of chromatin in the nucleus.
Professor, BIO5 Institute, Professor, Environmental Science, Professor, Plant Sciences
Martha Hawes is well known for her work on root border cells. Her entire career has focused on changing this perception and now border cells are described in numerous botany textbooks. Dr. Hawes has been very creative in designing experiments to understand the basic biology of this unique cell type especially in light of how border cells fight plant disease. Considering that the root tip serves as one of the major sources of root exudates that can attract microbial pathogens, the fact that this exceptionally vulnerable region of the root is protected from infection by the border cells is a real paradigm shift, especially via the mechanism.
Associate Professor, BIO5 Institute, Associate Professor, Clinical Translational Sciences, Associate Professor, Medicine
Louise Hecker’s research is focused on understanding why the process of regenerative biology and mechanisms of tissue injury-repair "goes awry" in aging. She is working to identifying novel pathways that can be targeted to reverse age-associated diseases, such as Idiopathic pulmonary fibrosis (IPF).
Associate Professor, BIO5 Institute, Associate Professor, Basic Medical Sciences, Associate Professor, Clinical Translational Sciences, Associate Professor, Obstetrics and Gynecology
Professor, Applied BioSciences - GIDP, Professor, BIO5 Institute, Professor, Plant Sciences
My research is directed at producing enhanced traits in soybean that improves its use and sustainability to provide for growing global needs. In soybeans have produced enhanced seeds that contain much more protein content while minimizing or eliminating several food allergens and anti-nutritional proteins. This will provide better food and animal feed.
Associate Professor, Applied Mathematics - GIDP, Associate Professor, BIO5 Institute, Associate Professor, Electrical and Computer Engineering, Associate Professor, Entomology / Insect Science - GIDP, Associate Professor, Neuroscience, Associate Professor, Neuroscience - GIDP
Regents Professor Emeritus, Professor Emeritus
Our research is centered on the prevention and treatment of our major degenerative diseases. We concentrate on peptide hormones and neurotransmitters and their receptors that are involved in these major diseases. Specific potential applications include pigmentary disorders, melanoma cancer, feeding disorders, pain, sexual function and motivation, and neurodegenerative diseases such as Alzheimer's, Parkinson's, etc.
Director, Biostatistics - Phoenix Campus, Professor, BIO5 Institute, Professor, Public Health, Professor, Statistics-GIDP
Chengcheng Hu has worked on a broad range of areas including cancer, occupational health, HIV/AIDS, and aging. He has extensive collaborative research in conducting methodological research in the areas of survival analysis, longitudinal data, high-dimensional data, and measurement error. His current methodological interest, arising from studies of viral and human genetics and biomarkers, is to develop innovative methods to investigate the relationship between high-dimensional information and longitudinal outcomes or survival endpoints.
Professor, BIO5 Institute, Professor, Pharmacology and Toxicology
The Hulme group is focused on small molecule drug design and developing enabling chemical methodologies to expedite the drug discovery process. The development of small molecule inhibitors of kinases is of particular interest.
Professor, BIO5 Institute, Professor, Ecology and Evolutionary Biology, Professor, Entomology, Chair, Entomology / Insect Science - GIDP
Molly Hunter works to understand the role of heritable microbial symbionts in the biology of herbivorous arthropod, or pest biology. Current projects include: Investigating Rickettsia in the sweet potato whitefly, Bemisia tabaci, and investigating interactions between Cardinium and Wolbachia, in whitefly parasitoids in the genus Encarsia and Eretmocerus.
Associate Director, BIO5 Institute, Professor, BIO5 Institute, Professor, Medicinal Chemistry-Pharmaceutical Sciences, Professor, Medicinal Chemistry-Pharmacology and Toxicology, Professor, Cancer Biology - GIDP
Laurence Hurley's long-time research interest is in molecular targeting of DNA, first by covalent binders (CC-1065 and psorospermin), then as compounds that target protein–DNA complexes (pluramycins and Et 743), and most recently as four-stranded DNA structures (G-quadruplexes and i-motifs). He was the first to show that targeting G-quadruplexes could inhibit telomerase (Sun et al. [1997] J. Med. Chem., 40, 2113) and that targeting G-quadruplexes in promoter complexes results in inhibition of transcription (Siddiqui-Jain et al. [2002] Proc. Natl. Acad. Sci. U.S.A., 99, 11593).
Assistant Professor, Agricultural-Biosystems Engineering, Assistant Professor, BIO5 Institute, Assistant Professor, Genetics - GIDP, Assistant Professor, Statistics-GIDP, Clinical Instructor, Pharmacy Practice-Science
Our lab focuses on large-scale –omics datasets, high-throughput computing, and big data analytics. We leverage these technologies to answer questions related to the relationship between microbes, their hosts, and the environment. In particular, we focus on viral-host interactions and co-evolution given environmental factors (i) in aquatic systems and (ii) for phage treatment of diabetic foot ulcers.
Assistant Professor, Immunobiology, Assistant Professor, BIO5 Institute
Metals such as calcium and iron are essential to living organisms. Some metals in excess, like copper, are detrimental to bacteria. My laboratory studies this phenomenon in Streptococcus pneumoniae to find novels method for killing pathogenic bacteria.
Associate Professor, Applied Mathematics - GIDP, Associate Professor, BIO5 Institute, Associate Professor, Genetics - GIDP, Professor, Computer Science
John Kececioglu's research is in applied algorithms, with an emphasis on bioinformatics and computational biology, including: multiple sequence alignment, inverse parametric alignment, sequence assembly, and genome rearrangement. Software developed by his group includes Opal, a tool for multiple sequence alignment, Facet, a tool for alignment accuracy estimation, InverseOpt, a library for inverse parametric optimization, Ipa, a tool for inverse sequence alignment, and AlignAlign, a tool for optimally aligning alignments.
Professor, Anesthesiology, Professor, BIO5 Institute, Professor, Neuroscience - GIDP, Professor, Pharmacology
The focus of my laboratory’s’ research is to understand how ion channels, specifically, voltage-gated calcium and sodium channels, are regulated by novel protein interactions. Recent studies in my laboratory have focused on targeting protein-protein interactions with biologics (peptide aptamers) and small molecules; testing the activity of these novel chemical entities in biochemical and immunofluorescent-based assays of trafficking; examining their protein interaction signatures; testing them with whole cell voltage-clamp electrophysiology and voltage- and calcium sensitive fluorescence-based imaging. Regulating these protein networks to modulate the activity of ion channels in neurodegenerative diseases (Chronic Pain, Migraine, and Neurofibromatosis) is a key focus of the laboratory.
Assistant Professor, BIO5 Institute, Assistant Professor, Biomedical / Materials Science Engineer, Assistant Professor, Biomedical Engineering
Minkyu Kim's research interests are in the areas of biopolymers and biomaterials for advanced national defense and healthcare. He is currently working to develop functional biopolymer materials for the treatment of antimicrobial-resistance diseases and atherosclerosis.
Adjunct Associate Professor, Nursing, Assistant Professor, Medicine - (Research Scholar Track), Associate Professor, BIO5 Institute, Associate Professor, Genetics - GIDP, Associate Professor, Pharmacology and Toxicology, Associate Professor, Public Health, Interim Associate Dean, Academic Programs and Faculty Affairs
Walter Klimecki's research program involves the balance between the particular DNA sequence “versions” of genes that we inherit from our ancestors, and the particular environmental exposures that we experience throughout our lives. The Klimecki lab studies diseases resulting from human exposure to arsenic, contributing to a better understanding of the inherited genetic differences between people that result in altered chemical processing of arsenic after it enters the body.
Assistant Professor, BIO5 Institute, Assistant Professor, Genetics - GIDP, Assistant Professor, Public Health
I use human genetic data to find associations of genetic markers with traits and diseases, to shed light on disease pathophysiology, causal pathways, and health disparities, and to inform personalized medicine.
Coordinator, Bac/Est Resource Center
We are a plant genomics lab who specialize in whole genome sequencing and assembly; with analyses of structural variation, gene modeling and transcriptomes. Our work on major projects of rice, corn, barley, etc, allows us to share our technical expertise with other researchers.
Associate Professor, Immunobiology, Associate Professor, BIO5 Institute, Associate Professor, Genetics - GIDP
Michael Kuhns' research program is focused on (i) increasing our basic understanding of how T cell fate decisions are made (e.g. development, activation, differentiation, effector functions), and (ii) increasing their working knowledge of how to manipulate these decisions to direct T cells towards a desired outcome, such as increasing responses to vaccines or tumors, preventing transplant rejection, or attenuating autoimmunity.
Assistant Professor, Aerospace-Mechanical Engineering, Assistant Professor, BIO5 Institute, Assistant Professor, Biomedical Engineering
Investigator, Center for Toxicology, Professor, BIO5 Institute, Professor, Cellular and Molecular Medicine, Professor, Public Health
We are interested in the effects of early life exposures to environmental toxicants on lung growth and development. We determine if the early life exposures leads to adult disease.
Assistant Professor, BIO5 Institute, Assistant Professor, Clinical Translational Sciences, Assistant Professor, Immunobiology, Associate Professor, Cellular and Molecular Medicine, Associate Professor, Medicine
Julie Ledford's research focuses on respiratory disease, and genetic and molecular mechanisms of allergic airway diseases in children.
Professor, BIO5 Institute, Professor, Entomology, Professor, Entomology / Insect Science - GIDP
Xianchun Li's research aims to use genetics to shed light on the defense signaling of plants and the counterdefense of herbivorous insects, which may result in the design of new insecticides for crops like corn, in defense against the corn earworm. Additionally, Dr. Li's research is to define, globally, the regulatory triangle between nuclear receptors (NRs), their ligands, and cytochrome P450s (P450s) in Drosophila melanogaster, and to investigate the molecular mechanisms of Bt and conventional insecticide resistance.
Assistant Dean, Graduate Education, Professor, BIO5 Institute, Professor, Cancer Biology - GIDP, Professor, Nutritional Sciences, Professor, Physiological Sciences - GIDP
Kirsten Limesand's research program has its foundation in radiation-induced salivary gland dysfunction; mechanisms of damage, clinical prevention measures, and restoration therapies. They utilize a number of techniques including: genetically engineered mouse models, real-time RT/PCR, immunoblotting, immunohistochemistry, primary cultures, siRNA transfections, and procedures to quantitate salivary gland physiology and integrate this information in order to understand the complete system.
Chair, Institutional Animal Care-USE Committee, Director, Agriculture Research Complex, Professor, Animal and Comparative Biomedical Sciences, Professor, BIO5 Institute, Professor, Obstetrics and Gynecology, Professor, Physiological Sciences - GIDP
Our current research program use an integrative approach at the whole animal, isolated organ, cellular and molecular levels to investigate developmental adaptations in pancreatic β-cells and insulin sensitivity that result from early life risk factors, such as intrauterine growth restriction, and increase risk of glucose intolerance and Diabetes in later life.
Associate Professor, Cellular and Molecular Medicine, Associate Professor, BIO5 Institute, Associate Professor, Immunobiology
Associate Director, Shared Resources, Associate Professor, Pharmacology, Director, Aribi Institute, Professor, BIO5 Institute, Professor, Biomedical Engineering, Professor, Physiological Sciences - GIDP, Professor, Physiology
Precise diagnosis and treatment of disease requires an ability to target agents to specific tissues and cell types within those tissues. We are developing agents that exhibit cell type specificity for these purposes.
Advisor, CALS' Office of the Assoc Dean - Research for Cyber Initiatives in Agricultural / Life - Vet Science, Associate Professor, Agricultural-Biosystems Engineering, Associate Professor, BIO5 Institute, Associate Professor, Genetics - GIDP, Associate Professor, Plant Science
Associate Professor, BIO5 Institute, Associate Professor, Clinical Translational Sciences, Associate Professor, Evelyn F Mcknight Brain Institute, Associate Professor, Medicine, Associate Professor, Molecular and Cellular Biology, Associate Professor, Neurology, Associate Professor, Neuroscience - GIDP, Associate Professor, Physiological Sciences - GIDP
Interim Director, Institute of the Environment, Professor, BIO5 Institute, Professor, Environmental Science-Ext, Professor, Pharmaceutical Sciences, Professor, Pharmacology and Toxicology
Assistant Professor, BIO5 Institute, Assistant Professor, Chemistry and Biochemistry-Sci
Professor, Ecology and Evolutionary Biology, Professor, Applied Mathematics - GIDP, Professor, BIO5 Institute, Professor, Genetics - GIDP, Professor, Psychology, Professor, Statistics-GIDP
Associate Professor, BIO5 Institute, Associate Professor, Ecology and Evolutionary Biology, Associate Professor, Entomology
Understanding how genes and genomes are shaped over many generations by the environment in which organisms live in. We also aim to examine how these changes accumulate and might facilitate the genetic divergence between populations and eventually possibly the origin of species.
Assistant Professor, Cancer Biology - GIDP, Assistant Professor, Cellular and Molecular Medicine, Assistant Professor, Genetics - GIDP, Research Associate Professor, Medicine
Assistant Professor, BIO5 Institute, Assistant Professor, Molecular and Cellular Biology, Assistant Professor, Pediatrics, Assistant Professor, Cancer Biology - GIDP
Assistant Professor, BIO5 Institute, Assistant Professor, Optical Sciences
Associate Professor, Ecology and Evolutionary Biology, Associate Research Professor, Curator, Herbarium
Chief, Division of Gastroenterology, Professor, Medicine
Assistant Professor, BIO5 Institute, Assistant Professor, Ecosystem Genomics, Assistant Professor, Genetics - GIDP, Assistant Professor, Global Change - GIDP, Assistant Professor, Hydrology / Atmospheric Sciences, Director, Biosphere 2 - Tropical Rain Forest
We aim to constrain the microbial drivers of soil-atmosphere trace gas fluxes across a range of scales. We constrain the genetic traits for trace gas metabolism and develop new tools for measuring genes and gases in heterogenous soil systems. New understanding is evaluated across a range of model to natural ecosystems where microbial trace gas cycling occurs in the context of environmental forcings and interactions.
Assistant Professor, Assistant Professor, BIO5 Institute, Assistant Professor, Neurology, Assistant Professor, Neuroscience - GIDP, Assistant Professor, Speech and Hearing Science
Professor, Applied Mathematics - GIDP, Professor, BIO5 Institute, Professor, Cancer Biology - GIDP, Professor, Genetics - GIDP, Professor, Molecular and Cellular Biology, Professor, Chemistry and Biochemistry-Sci
We investigate how proteins work in healthy organisms and how they fail in disease. We determine the atomic structures of proteins and the underlying biochemistry that gives rise to protein function. We also develop new proteins as drug targets for treating cancer and cardiovascular disease.
Associate Director, School of Plant Sciences, Associate Professor, Applied BioSciences - GIDP, Associate Professor, BIO5 Institute, Associate Professor, Genetics - GIDP, Associate Professor, Plant Sciences
Co-Director, Arizona Center on Aging, Department Head, Immunobiology, Professor, BIO5 Institute, Professor, Immunobiology, Professor, Medicine, Professor, Nutritional Sciences, Professor, Genetics - GIDP, Professor, Neuroscience - GIDP
Professor, BIO5 Institute, Professor, Chemistry and Biochemistry-Sci
Professor, BIO5 Institute, Professor, Genetics - GIDP, Professor, Plant Sciences
Professor, BIO5 Institute, Professor, Chemistry and Biochemistry, Professor, Chemistry and Biochemistry-Sci, Professor, Immunobiology
How we sense and react to our environment is communicated in the cell by vast networks of highly dynamic, interacting proteins. These interactions are regulated in both space and time, and it is this tight regulation that allows signals from outside of the cell to be rapidly and precisely transmitted to the nucleus leading to the appropriate, and healthy, cellular response. My research integrates structural biology, biophysics and biochemistry in order to understand how these signals and to develop novel drugs for the treatment of cancer, autoimmune disorders and antibiotic resistance.
Associate Professor, Applied BioSciences - GIDP, Associate Professor, Plant Science, Professor, Molecular and Cellular Biology, Associate Professor, Genetics - GIDP
Professor, Chemistry and Biochemistry, Professor, BIO5 Institute, Professor, Chemistry and Biochemistry-Sci
Professor, BIO5 Institute, Professor, Chemistry and Biochemistry-Sci, Professor, Neuroscience - GIDP, Professor, Pharmacology and Toxicology
Professor, Agricultural-Biosystems Engineering, Professor, BIO5 Institute, Professor, Plant Sciences
Assistant Professor, Immunobiology, Research Fellow, BIO5 Institute
All viruses hijack host cell machinery to facilitate their replication. My lab investigates how the production of infectious viral progeny relies on host metabolism. Our overall goal is to guide the development of novel antiviral therapies using information regarding how viruses hijack host metabolism.
Associate Vice President, Precision Health Sciences, Associate Vice President, Research, Director, MD/PhD Program, Professor, Internal Medicine, Professor, Medicine
Associate Professor, Animal and Comparative Biomedical Sciences, Associate Professor, BIO5 Institute
Associate Professor, Animal and Comparative Biomedical Sciences, Associate Professor, BIO5 Institute, Associate Professor, Nutritional Sciences, Associate Professor, Physiological Sciences - GIDP
Renquist Lab Research aims to address the causes and consequent diseases of obesity. To this end we have research focused on 1) type 2 diabetes and obesity associated hypertension, 2) development of effective, ligand-directed, chemotherapeutic for cancer, and 3) central nervous system control of visceral blood flow and food intake.
Professor, BIO5 Institute, Professor, Cellular and Molecular Medicine, Professor, Entomology / Insect Science - GIDP, Professor, Neurology, Professor, Neuroscience, Professor, Genetics - GIDP, Professor, Neuroscience - GIDP
Distinguished Professor, Professor, BIO5 Institute, Professor, Ecology and Evolutionary Biology
Associate Head, Faculty Development, Associate Professor, BIO5 Institute, Associate Professor, Cancer Biology - GIDP, Associate Professor, Cellular and Molecular Medicine, Associate Professor, Molecular and Cellular Biology, Associate Professor, Genetics - GIDP
Associate, Center for Toxicology, Professor, Animal and Comparative Biomedical Sciences, Professor, BIO5 Institute, Professor, Nutritional Sciences, Professor, Cancer Biology - GIDP
Assistant Professor, Cellular and Molecular Medicine, Research Fellow, BIO5 Institute
My laboratory aims to identify the genetic and environmental reasons that certain individuals are predisposed to develop complex diseases like heart disease. We use new technologies, experimental, and computational approaches to identify molecular patterns indicative of disease predisposition.
Associate Professor, BIO5 Institute, Associate Professor, Biomedical Engineering, Associate Professor, Materials Science and Engineering
Professor, BIO5 Institute, Professor, Biomedical Engineering, Professor, Electrical and Computer Engineering
Professor, BIO5 Institute, Professor, Ecology and Evolutionary Biology
Associate Professor, BIO5 Institute, Associate Professor, Ecology and Evolutionary Biology, Associate Professor, Entomology, Associate Professor, Entomology / Insect Science - GIDP, Associate Professor, Genetics - GIDP, Associate Professor, Molecular and Cellular Biology, Associate Professor, Neuroscience - GIDP
Professor, BIO5 Institute, Professor, Plant Sciences
Assistant Professor, BIO5 Institute, Assistant Professor, Chemistry and Biochemistry - Med, Assistant Professor, Chemistry and Biochemistry-Sci, Assistant Professor, Neuroscience - GIDP
Professor, Applied Mathematics - GIDP, Professor, BIO5 Institute, Regents Professor
Associate Professor, Cancer Biology - GIDP, Associate Professor, Immunobiology, Associate Professor, Nutritional Sciences, Associate Professor, Pediatrics, Associate Professor, Physiological Sciences - GIDP
Assistant Research Director, Arizona Center for Integrative Medicine, Associate Professor, Medicine - (Research Scholar Track)
The focus of my work is development of "Lab-in-a-Bandage" disposable skin patches. These "micro-labs" are designed to (1) collect a series of tiny sweat samples, (2) perform a chemical analysis for medically important target molecules, and (3) transmit the measurements to where ever they are needed. For example, this technology will enable people to apply their own skin patch, allowing lab tests to be carried out continuously as they go about their daily business, without blood draws or clinic visits.
Associate Professor, BIO5 Institute, Associate Professor, Cancer Biology - GIDP, Associate Professor, Genetics - GIDP, Associate Professor, Pharmacology and Toxicology
Chief, Science / Technology Officer, Professor, BIO5 Institute, Professor, Chemical and Environmental Engineering, Professor, Environmental Science-Ext, Professor, Public Health
I am an Environmental Engineering with training in Toxicology and Chemistry. My primary field of expertise is identification, health assessment, and fate of environmental pollutants. I also work in the field of drug discovery from natural products. My team and I also develop novel analytical techniques for ultra-trace analysis, including on-line sensor systems.
Director, Microbial Pathogenesis Program, Professor, Animal and Comparative Biomedical Sciences, Professor, BIO5 Institute, Professor, Biochemistry/Molecular Biophysics, Professor, Genetics - GIDP, Professor, Immunobiology, Professor, Molecular and Cellular Biology
How do bacteria "talk" to the body? How does the body reply to the microbe? How does this conversation affect your health and well being?
Research Associate Professor, BIO5 Institute
Director, Animal and Comparative Biomedical Sciences, Endowed Chair, Weiler, Professor, Animal and Comparative Biomedical Sciences, Professor, BIO5 Institute, Professor, Entomology, Professor, Entomology / Insect Science - GIDP
Dr. Stock’s research centers on the study day of hosts-microbe interactions ranging from mutualistic to antagonistic.The model system for her work are entomopathogenic nematodes, their bacterial symbionts and the insect hosts both of these organisms interact with.
Assistant Professor, BIO5 Institute, Associate Professor, Pharmacology and Toxicology, Associate Professor, Cancer Biology - GIDP
Department Head, Entomology, Professor, BIO5 Institute, Professor, Entomology, Regents Professor, Professor, Entomology / Insect Science - GIDP
Assistant Professor, BIO5 Institute, Assistant Professor, Chemistry and Biochemistry
Distinguished Outreach Professor, Faculty Director, Diversity and Inclusion, Professor, Applied BioSciences - GIDP, Professor, BIO5 Institute, Professor, Genetics - GIDP, Professor, Molecular and Cellular Biology, Professor, Plant Sciences
Associate Professor, Anthropology
Assistant Professor, BIO5 Institute, Assistant Professor, Cellular and Molecular Medicine
We combine chemical and computer vision approaches to discover how regenerative tissues process environmental information to promote accurate cell fate decisions and prevent uncontrolled cell growth.
Assistant Research Scientist, BIO5 Institute, Staff Scientist
Assistant Professor, Agricultural-Biosystems Engineering, Assistant Professor, Animal and Comparative Biomedical Sciences, Assistant Professor, BIO5 Institute, Assistant Professor, Ecosystem Genomics, Assistant Professor, Genetics - GIDP
We study the biodiversity, biogeography, evolutionary origins, and ecological roles of plant-associated microorganisms. We use a combination of traditional culture-based microbiology, functional assays, and next-generation 'omics tools to study microbial symbiont communities in diverse lineages of land plants at scales ranging from local to global. We are interested in characterizing the biotic and abiotic factors shaping the assembly of plant-associated fungal communities, how community structure and diversity impacts ecosystem function, and the evolutionary dynamics of fungal symbiont evolution in the context of closely related pathogens and saprotrophs.
Director, Ligand Discovery Laboratory, Research Associate Professor, Pharmacology, Research Professor
Associate Professor, BIO5 Institute, Associate Professor, Pharmacology and Toxicology, Associate, Center for Toxicology, Co-Director, Bachelor of Science - Pharmaceutical Sciences Program
Associate Professor, BIO5 Institute, Associate Professor, Molecular and Cellular Biology, Associate Professor, Optical Sciences, Associate Professor, Physics, Associate Professor, Applied Mathematics - GIDP
Associate Professor, Animal and Comparative Biomedical Sciences, Associate Professor, BIO5 Institute
Ninety children die every hour due to diarrhea. My laboratory uses the latest technology to understand how bacteria cause diarrhea in children. In addition to providing clues for new ways to prevent disease, our research helps us understand how the body maintains good health.
Adjunct Professor, Animal and Comparative Biomedical Sciences, Adjunct Professor, Molecular and Cellular Biology, Professor, Applied Mathematics - GIDP, Professor, BIO5 Institute, Professor, Ecology and Evolutionary Biology, Professor, Entomology / Insect Science - GIDP, Professor, Genetics - GIDP, Professor, Plant Sciences, Professor, Public Health, Professor, Statistics-GIDP
Director, Drug Discovery Program, Professor, Pharmacology and Toxicology
Assistant Professor, Applied BioSciences - GIDP, Assistant Research Professor, Director, Viper Institute
Assistant Research Scientist, Entomology
Bud Antle Endowed Chair For Excellence, Agriculture-Life Sciences, Director, Plant Genomics Institute, Professor, BIO5 Institute, Professor, Ecology and Evolutionary Biology, Professor, Plant Science, Regents Professor
Harnessing 15MY of natural variation in the genus Oryza (rice) to help solve the 10-billion people question: i.e. how do we feed our world without destroying our world.
Associate Professor, Applied Mathematics - GIDP, Associate Professor, BIO5 Institute, Associate Professor, Biomedical Engineering, Associate Professor, Neuroscience - GIDP, Associate Professor, Optical Sciences, Professor, Medical Imaging
We develop cutting-edge imaging technology, integrating light, ultrasound and electricity, to diagnose and treat diseases ranging from epilepsy to breast cancer. Novel sources for ultrasound contrast include optical and microwave absorption, mechanical strain, and electrical current. We visualize electrical brain “stormsˮ during uncontrollable seizures and envision “smartˮ photoacoustic agents that seek-and-destroy deadly tumors.
Assistant Professor, BIO5 Institute, Assistant Professor, Surgery
Associate Director, Microbiome, Department Head, Ecology and Evolutionary Biology, Professor, BIO5 Institute, Professor, Ecology and Evolutionary Biology, Professor, Genetics - GIDP
Associate Professor, Aerospace-Mechanical Engineering, Associate Professor, BIO5 Institute
Associate Professor, Plant Sciences, Associate Professor, BIO5 Institute
Professor, BIO5 Institute, Professor, Genetics - GIDP, Professor, Molecular and Cellular Biology, Professor, Plant Science
Professor, BIO5 Institute, Professor, Pharmacology and Toxicology, Professor, Cancer Biology - GIDP
Professor, Agricultural-Biosystems Engineering, Professor, Animal and Comparative Biomedical Sciences, Professor, BIO5 Institute, Professor, Biomedical Engineering, Professor, Chemistry and Biochemistry-Sci
Professor, Applied BioSciences - GIDP, Professor, BIO5 Institute, Professor, Cellular and Molecular Medicine, Professor, Genetics - GIDP, Professor, Molecular and Cellular Biology, Professor, Neurology, Professor, Neuroscience, Professor, Neuroscience - GIDP
We are working to uncover the molecular mechanisms of aging and neurodegenerative diseases using a combination of genetic, computational and pharmacological tools, and a diverse array of experimental models. We also seek to develop therapies for ALS and related neurodegenerative diseases.
Professor, Professor, BIO5 Institute, Professor, Cancer Biology - GIDP
Professor, Aerospace-Mechanical Engineering, Professor, BIO5 Institute, Professor, Biomedical Engineering