I am interested in exploring innovative and useful chemical tools and small molecules as probes to study biology and as therapeutics for disease treatment. My laboratory has been particularly interested in exploring chemical tools to address the important biological questions. I am a well-established investigator with over 20 years research experience and more than 240 peer reviewed publications (H-index: 72) in the fields of organic and medicinal chemistry and chemical biology. The small molecule-based fluorescence probes developed from my laboratory have been widely used by biomedical researchers as tools to study the cellular and molecular mechanisms. One of the small molecules discovered by my laboratory has been licensed to the Andaman Therapeutics for clinical trials as a new class of anticancer therapy.