Viruses
Associate Professor, BIO5 Institute, Associate Professor, Cancer Biology - GIDP, Associate Professor, Immunobiology, Associate Professor, Molecular and Cellular Biology

We aim to understand the mechanisms of HPV infection, the cellular responses to HPV infection, and how the interplay between host and virus influences the outcome

Professor, BIO5 Institute, Professor, Genetics - GIDP, Professor, Immunobiology, Professor, Plant Sciences, Professor, Applied BioSciences - GIDP
Upon infection, viruses must transport their genomes into cells and produce progeny, often under a strict time deadline. We study how the viral proteins interact with with each other and with host cell proteins to efficiently accomplish these processes.
Member of the Graduate Faculty, Professor, BIO5 Institute, Professor, Cancer Biology - GIDP, Professor, Cellular and Molecular Medicine, Professor, Genetics - GIDP, Professor, Immunobiology, Professor, Molecular and Cellular Biology
Dr. Goodrum's long-standing research focus is to understand the molecular virus-host interactions important to human cytomegalovirus (CMV) latency and persistence in the host. She has focused on identifying viral and host determinants mediating the switch between latent and replicative states. The goal of her research program is to define the mechanistic underpinnings of HCMV latency and reactivation to lay the foundation for clinical interventions to control CMV disease in all settings.
Member of the Graduate Faculty, Professor, Professor, BIO5 Institute, Professor, Chemistry and Biochemistry - Med, Professor, Chemistry and Biochemistry-Sci, Professor, Genetics - GIDP
The Horton lab uses biophysical, biochemical, and molecular biology to study protein-DNA interactions and filament formation by enzymes. Current projects include the investigation of mechanisms of disease caused by the Human Parvovirus B19, and advantages of filament formation by enzymes such as the sequence specific DNA endonuclease SgrAI, and the important metabolic enzyme PFK.
Assistant Professor, Cancer Biology - GIDP, Assistant Professor, Immunobiology, Member of the Graduate Faculty, Research Fellow, BIO5 Institute
All viruses hijack host cell machinery to facilitate their replication. My lab investigates how the production of infectious viral progeny relies on host metabolism. Our overall goal is to guide the development of novel antiviral therapies using information regarding how viruses hijack host metabolism.
Assistant Professor, BIO5 Institute, Assistant Professor, Cancer Biology - GIDP, Assistant Professor, Genetics - GIDP, Assistant Professor, Immunobiology, Assistant Professor, Virology
Associate Director, Microbiome, Department Head, Ecology and Evolutionary Biology, Professor, BIO5 Institute, Professor, Ecology and Evolutionary Biology, Professor, Genetics - GIDP