Research being done at the University of Arizona is seeking to help prevent dementia after a stroke, using cyclodextrin to trap cholesterol in the brain.

UArizona researchers discovered a potential treatment to reduce the risk of post-stroke dementia, which may be influenced by the immune response to dead brain tissue left in the wake of a stroke, according to a new study.

The BIO5 Postdoctoral Fellowship grants financial support and facilitates mentorship to enrich awardees’ research aims and career development.

Dr. Kristian Doyle leads a team at UArizona to study the connection between resulting inflammation after stroke, and the development of dementia. the inflammatory response at the site of the stroke which may be causing the condition.

The risk of developing dementia after a stroke may be reduced by a drug that could help immune cells process stroke-generated, cholesterol-rich brain debris.

Dr. Kristian Doyle, BIO5 member and assistant professor in the Department of Immunobiology, has discovered this liquefied brain tissue is toxic and can slowly leak into the healthy portion of the brain, causing harm. The discovery may help develop new tre