Julie Elizabeth Miller
Assistant Professor
Assistant Professor, BIO5 Institute
Assistant Professor, Neurology
Assistant Professor, Neuroscience - GIDP
Assistant Professor, Speech and Hearing Science
Primary Department
Department Affiliations
(520) 626-0100
Research Interest
My laboratory studies neurogenetic mechanisms which underlie normal and abnormal motor speech using the zebra finch songbird. My particular focus is to investigate molecular and cellular pathways altered by speech disorders associated with neurological diseases such as Parkinson’s Disease. To carry out these investigations, we use a combination of behavioral, genetic, biochemical and electrophysiological approaches that enable us to link changes at the molecular/cellular levels to alterations in neural circuits for song behavior. In addition to my laboratory studies, I have active collaborations with researchers working in a variety of mammalian species including clinicians. The end goal is to leverage the advantages offered by each species and an array of biological tools to further advance our understanding of speech mechanisms.

Publications

Miller, J. E. (2015). Reduced vocal variability in a zebra finch model of dopamine depletion: implications for Parkinson disease.. Physiological Reports, 3(11). doi:10.14814/phy2.12599
Hilliard, A., Miller, J., Fraley, E., Horvath, S., & White, S. (2012). Molecular Microcircuitry Underlies Functional Specification in a Basal Ganglia Circuit Dedicated to Vocal Learning. Neuron, 73, 537-552.
Grant, L. M., Richter, F., Miller, J., White, S., Fox, C., Chesselet, M., & Ciucci, M. (2014). Vocalization deficits in mice over-expressing alpha-synuclein, a model of pre-manifest Parkinson's disease.. Behav Neurosci, 128, 110-121.
Hilliard, A. T., Miller, J., Horvath, S., & White, S. (2012). Distinct Neurogenomic States in Basal Ganglia Subregions Relate Differently to Singing Behavior in Songbirds. PloS Comput Biol, 8(11), e1002773.