Spaite, D. W., Hu, C., Bobrow, B. J., Chikani, V., Barnhart, B., Gaither, J. B., Denninghoff, K. R., Adelson, P. D., Keim, S. M., Viscusi, C., Mullins, T., & Sherrill, D. (2017). The Effect of Combined Out-of-Hospital Hypotension and Hypoxia on Mortality in Major Traumatic Brain Injury. ANNALS OF EMERGENCY MEDICINE, 69(1), 62-72.
BIO5 Collaborators
Kurt R Denninghoff, Chengcheng Hu
Chikani, V., Spaite, D. W., Smith, J. J., Curry, M., Mhayamagru, M., Barnhart, B. J., Adelson, P. D., Viscusi, C. D., Denninghoff, K. R., Bobrow, B. J., & Gaither, J. B. (2016). Elevated Initial Trauma Center Body Temperatures Are Associated With Poor Non-Mortality Outcomes Following Major Traumatic Brain Injury. Prehospital Emergency Care.
Appel, J. E., Appel, J. E., Farrell, I. J., Farrell, I. J., Stoneking, L. R., Stoneking, L. R., Denninghoff, K. R., & Denninghoff, K. R. (2015). Meta-analysis of point of care D-dimers in the emergency department. Annals of Emergency Medicine.
Spaite, D. W., Hu, C., Bobrow, B. J., Chikani, V., Sherrill, D., Barnhart, B., Gaither, J. B., Denninghoff, K. R., Viscusi, C., Mullins, T., & Adelson, P. D. (2017). Mortality and Prehospital Blood Pressure in Patients With Major Traumatic Brain Injury: Implications for the Hypotension Threshold. JAMA surgery, 152(4), 568-74. doi:10.1001/jamasurg.2016.4686
BIO5 Collaborators
Kurt R Denninghoff, Chengcheng Hu
Current prehospital traumatic brain injury guidelines use a systolic blood pressure threshold of less than 90 mm Hg for treating hypotension for individuals 10 years and older based on studies showing higher mortality when blood pressure drops below this level. However, the guidelines also acknowledge the weakness of the supporting evidence.
Spaite, D. W., Stolz, U., Chikani, V., Bobrow, B. J., Sotelo, M., Barnhart, B. J., Denninghoff, K. R., Gaither, J. B., Viscusi, C. D., Adelson, D. P., Sherrill, D. L., & Harden, D. (2016). The Influence of Prehospital Hypotension and Hypoxia on Non-Mortality Outcomes in Patients with Major Traumatic Brain Injury. Prehospital Emergency Care.