Scott B Going

Scott B Going

Director, School of Nutritional Sciences and Wellness
Professor, Nutritional Sciences
Professor, Public Health
Professor, Physiology
Professor, Physiological Sciences - GIDP
Professor, BIO5 Institute
Primary Department
Department Affiliations
(520) 626-3432

Work Summary

Scott Going is an expert in models and methods for assessment of changes in body composition during growth, and with aging, and is currently investigating the effects of chronic exercise versus hormone replacement therapy on bone, soft tissue composition and muscle strength in postmenopausal women, as well as the role of exercise in obesity prevention in children.

Research Interest

Current projects include:The Bone, Estrogen and Strength Training (BEST) study, a randomized prospective study of the effects of hormone replacement therapy on bone mineral density, soft tissue composition, and muscle strength in postmenopausal women (National Institutes of Health). The Profile-based Internet-linked Obesity Treatment study (PILOT), a randomized study of internet support for weight maintenance after weight loss in peri-menopausal women (National Institutes of Health). The Trial of Activity for Adolescent Girls (TAAG) study, a multi-center, school-based activity trial designed to prevent the usual decline in physical activity in adolescent girls (National Institutes of Health). The Adequate Calcium Today (ACT) study, a randomized multi-center study of a behavioral intervention to promote healthy eating, calcium intake and bone development in adolescent girls (United States Department of Agriculture). The Healthy Weight in Adolescents study, a randomized, multi-center study of the effects of a science-based curriculum focused on concepts of energy balance on body weight and composition in adolescent boys and girls (United States Department of Agriculture). The KNEE study, a randomized clinical trial of the effects of resistance exercise on disease progression, pain, and functional capacity in osteoarthritis patients (National Institutes of Health). The STRONG study, a randomized clinical trial of the effects of resistance exercise and Remicaid on disease progression, pain, muscle strength and functional capacity in rheumatoid arthritis patients (Centocor, Inc.). Partners for Healthy Active Children, Campañeros Para Niños Sano y Actives, designed to create and implement research-based physical education and nutrition curricula at YMCA after-school programs and Sunnyside District elementary schools, in alignment with the State o Arizona , Health and Physical Activity standards (Carol M. White Physical Education Program CFDA #84.215F). Longitudinal Changes in Hip Geometry, an observational and experimental cohort study of changes in muscle mass, hip structural parameters and hip bone strength in middle-aged and older women in the Women's Healthy Initiative study (National Institutes of Health).


Going, S. B., Chen, Z., Alexander, G. E., Mandarino, L. J., Garcia, D. O., Bea, J. W., Raichlen, D. A., & Klimentidis, Y. C. (2017). Genome-wide association study of habitual physical activity in over 277,000 UK Biobank participants indentifies novel variants and genetic correlations with chronotype and obesity related traits. International Journal of Obesity.
BIO5 Collaborators
Zhao Chen, Scott B Going, Yann C Klimentidis
Klimentidis, Y. C., Bea, J. W., Lohman, T. G., Hsieh, P. S., Going, S. B., & Chen, Z. (2015). Resistance exercise intervention results in less weight loss among individuals at high genetic risk for obesity. International Journal of Obesity, 39(9), 1371-1375.
BIO5 Collaborators
Zhao Chen, Scott B Going, Yann C Klimentidis
Farr, J. N., Funk, J. L., Chen, Z., Lisse, J. R., Blew, R. M., Lee, V. R., Laudermilk, M., Lohman, T. G., & Going, S. B. (2011). Skeletal Muscle Fat Content Is Inversely Associated With Bone Strength in Young Girls. JOURNAL OF BONE AND MINERAL RESEARCH, 26(9), 2217-2225.
BIO5 Collaborators
Janet L Funk, Scott B Going
Higgins, K. J., Reid, P. M., Going, S. B., & Howell, W. H. (2007). Validation of bioimpedance spectroscopy to assess acute changes in hydration status. Medicine and Science in Sports and Exercise, 39(6), 984-990.

PMID: 17545889;Abstract:

PURPOSE: To validate bioimpedance spectroscopy (BIS) as a field method for measuring small, acute changes in extracellular water (ECW) during a fluid fast/rehydration manipulation. METHODS: Seventeen young adults (15 female, 2 male) participated in a 4-d fluid fast/rehydration protocol designed to induce acute changes in ECW. ECW change (ΔECW), measured by bioimpedance spectroscopy (BIS-ΔECW), was compared with ΔECW, measured by bromide dilution (Br-ΔECW), and change in body weight (ΔBW). RESULTS: Regardless of hydration status, BIS-ΔECW and Br-ΔECW were similar; during dehydration, the mean difference between these two methods was 0.16 kg (P = 0.61), and during rehydration, the mean difference was 0.58 kg (P = 0.06). Assuming that ΔECW = ΔBW, ΔECW as estimated from ΔBW differed significantly from Br-ΔECW, but not from BIS-ΔECW. In addition, BIS-ΔECW correlated significantly with ΔBW (r = 0.57 and 0.65 during dehydration and rehydration, respectively). However, the magnitude of ΔECW impacted the accuracy of BIS-ΔECW because BIS measures tended to overestimate ΔECW at values between 0.0 and 1.0 kg and to underestimate changes at values above 1.0 kg. CONCLUSION: These findings suggest that BIS provides an accurate estimate of ΔECW compared with bromide dilution during short-term changes in hydration. ©2007The American College of Sports Medicine.

C, U., Going, S. B., Turner, T., Stump, C. S., Roe, D., Hingle, M. D., & Kutob, R. M. (2017). Feasibility and efficacy of a family-focused, YMCA-based diabetes prevention program for youth. Pediatric Diabetes.