Scott B Going

Scott B Going

Director, School of Nutritional Sciences and Wellness
Professor, Nutritional Sciences
Professor, Public Health
Professor, Physiology
Professor, Physiological Sciences - GIDP
Professor, BIO5 Institute
Primary Department
Department Affiliations
Contact
(520) 626-3432

Work Summary

Scott Going is an expert in models and methods for assessment of changes in body composition during growth, and with aging, and is currently investigating the effects of chronic exercise versus hormone replacement therapy on bone, soft tissue composition and muscle strength in postmenopausal women, as well as the role of exercise in obesity prevention in children.

Research Interest

Current projects include:The Bone, Estrogen and Strength Training (BEST) study, a randomized prospective study of the effects of hormone replacement therapy on bone mineral density, soft tissue composition, and muscle strength in postmenopausal women (National Institutes of Health). The Profile-based Internet-linked Obesity Treatment study (PILOT), a randomized study of internet support for weight maintenance after weight loss in peri-menopausal women (National Institutes of Health). The Trial of Activity for Adolescent Girls (TAAG) study, a multi-center, school-based activity trial designed to prevent the usual decline in physical activity in adolescent girls (National Institutes of Health). The Adequate Calcium Today (ACT) study, a randomized multi-center study of a behavioral intervention to promote healthy eating, calcium intake and bone development in adolescent girls (United States Department of Agriculture). The Healthy Weight in Adolescents study, a randomized, multi-center study of the effects of a science-based curriculum focused on concepts of energy balance on body weight and composition in adolescent boys and girls (United States Department of Agriculture). The KNEE study, a randomized clinical trial of the effects of resistance exercise on disease progression, pain, and functional capacity in osteoarthritis patients (National Institutes of Health). The STRONG study, a randomized clinical trial of the effects of resistance exercise and Remicaid on disease progression, pain, muscle strength and functional capacity in rheumatoid arthritis patients (Centocor, Inc.). Partners for Healthy Active Children, Campañeros Para Niños Sano y Actives, designed to create and implement research-based physical education and nutrition curricula at YMCA after-school programs and Sunnyside District elementary schools, in alignment with the State o Arizona , Health and Physical Activity standards (Carol M. White Physical Education Program CFDA #84.215F). Longitudinal Changes in Hip Geometry, an observational and experimental cohort study of changes in muscle mass, hip structural parameters and hip bone strength in middle-aged and older women in the Women's Healthy Initiative study (National Institutes of Health).

Publications

Hongu, N., Hingle, M., Merchant, N., Orr, B., Going, S., Mosqueda, M., & Thomson, C. (2011). Dietary Assessment Tools Using Mobile Technology (Review Article). Topics in Clinical Nutrition (TICN), 26(4), 300-311.
Going, S. B., Massett, M. P., Hall, M. C., Bare, L. A., Root, P. A., Williams, D. P., & Lohman, T. G. (1993). Detection of small changes in body composition by dual-energy x-ray absorptiometry. American Journal of Clinical Nutrition, 57(6), 845-850.

PMID: 8503351;Abstract:

The ability of dual-energy x-ray absorptiometry (DEXA) to detect small changes in body composition was studied in 17 men and women during a dehydration-rehydration protocol. Scale weight (BW) and total mass (TM) from DEXA were highly related (r > 0.99) as were estimates of fat-free mass (r = 0.99) and percent fat (r = 0.97) from DEXA and densitometry. Changes in BW of ≈1.5 kg due to fluid loss and gain were highly correlated (r = 0.90) with both changes in TM and soft-tissue mass (STM) by DEXA but less so (r = 0.67) with changes in lean-tissue mass (LTM). Mean changes in TM, STM, and LTM were not different (P > 0.05) from changes in BW. Estimates of bone mass and fat were unaffected by changes in hydration. We conclude that DEXA is able to detect small individual changes in TM and STM and is also useful for detecting group changes in LTM.

Going, S., Thompson, J., Cano, S., Stewart, D., Stone, E., Harnack, L., Hastings, C., Norman, J., & Corbin, C. (2003). The effects of the Pathways Obesity Prevention Program on physical activity in American Indian children. Preventive Medicine, 37(SUPPL. 1), S62-S69.

PMID: 14636810;Abstract:

Background. Inadequate opportunities for physical activity at school and overall low levels of activity contribute to the high prevalence of overweight and obesity in American-Indian children. Methods. A school-based physical activity intervention was implemented which emphasized increasing the frequency and quality of physical education (PE) classes and activity breaks. Changes in physical activity were assessed using the TriTrac-R3D accelerometer in a subsample of 580 of the students (34%) randomly selected from the Pathways study cohort. Baseline measures were completed with children in second grade. Follow-up measurements were obtained in the spring of the fifth grade. Results. Intervention schools were more active (+6.3 to +27.2%) than control schools at three of the four sites, although the overall difference between intervention and control schools (∼10%) was not significant (P > 0.05). Boys were more active than girls by 17 to 21% (P ≤ .01) at both baseline and follow-up. Conclusions. Despite the trend for greater physical activity at three of four study sites, and an overall difference of ∼10% between intervention and control schools, high variability in accelerometer AVM and the opportunity to measure physical activity on only 1 day resulted in a the failure to detect the difference as significant. © 2003 American Health Foundation and Elsevier Science (USA). All rights reserved.

Cussler, E. C., Teixeira, P. J., Going, S. B., Houtkooper, L. B., Metcalfe, L. L., Blew, R. M., Ricketts, J. R., Lohman, J., Stanford, V. A., & Lohman, T. G. (2008). Maintenance of weight loss in overweight middle-aged women through the internet. Obesity, 16(5), 1052-1060.

PMID: 18309301;Abstract:

Objective: The purpose of this study was to compare weight regain in a group of perimenopausal women (48.0 ± 4.4 years old), randomized to a 12-month weight maintenance Internet intervention or to self-directed weight maintenance after a 4-month weight loss treatment. Methods and Procedures: After a 4-month behavioral weight loss program, 135 women were randomized to either Internet or self-directed groups. The Internet group (n = 66) used a website to gain information and complete logs concerning their weight, diet, and exercise progress over a 12-month follow-up. The 69 self-directed women had no contact with study staff. All women were measured for weight and body composition, and diet intake, and were interviewed using the 7-day physical activity questionnaires at baseline, 4 months, and 16 months. Results: At the end of the 12-month follow-up, the Internet and self-directed groups had regained on average 0.4 ± 5.0 kg and 0.6 ± 4.0 kg, respectively (P = 0.5). In within-group analyses, Internet diet-log entries were correlated with follow-up weight change (r = -0.29; P 0.05) and moderately with change in exercise energy expenditure (EEE; r = 0.44; P 0.01). Follow-up weight change was not correlated with change in dietary intake. Discussion: While significant weight loss was maintained over follow-up by both groups of women, Internet use did not surpass self-direction in helping to sustain weight loss. Among Internet users, Internet use was related to weight change and EEE. © 2008 The Obesity Society.

Teixeira, P. J., Sardinha, L. B., Going, S. B., & Lohman, T. G. (2001). Total and regional fat and serum cardiovascular disease risk factors in lean and obese children and adolescents. Obesity research, 9(8).

This study was conducted to evaluate the association of total and central adiposity with serum cardiovascular disease (CVD) risk factors in lean and obese Portuguese children and adolescents.