In the news / Cardiovascular

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Dr. Giuliana Repetti, a nationally accomplished young investigator in cardiovascular science, worked with BIO5 faculty Drs. Steven Goldman and Jil Tardiff. Dr. Repetti developed a patch that can be surgically implanted on the epicardial surface of the heart as a treatment for heart failure. She was recently awarded the nationally prestigious Sarnoff Cardiovascular Research Fellowship to work in a genetics lab at Harvard Medical School and Brigham and Women’s Hospital.
 
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As of April 28, more than 6,500 COVID-19 cases have been reported in the state of Arizona.

 
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The BIO5 Institute solicited COVID-19 research proposals for seed grants supplied by the Technology and Research Initiative Fund (TRIF).

 
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Dr. Carol Gregorio has been appointed to the roles of Interim Executive Director for UArizona Health Sciences Global and Online, and Assistant Vice Provost for Global Health Sciences. Dr. Gregorio is internationally recognized as a leader in heart muscle research. She joined the College of Medicine – Tucson faculty in 1996, and is the head of the Department of Cellular and Molecular Medicine. She also serves as the co-director of the Sarver Heart Center, director of the Molecular Cardiovascular Research Program, and member of the BIO5 Institute.
 
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The UArizona found itself at the center of many of the world's most captivating news stories in 2019. From its leadership role in capturing mankind's first image of a black hole to discovering a protein that prevents mosquitoes from hatching, opening the possibility of developing new drugs that could act as birth control for mosquito populations, UArizona led research generated international headlines this year.
 
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Acoustoelectric cardiac imaging, a new, noninvasive cardiac imaging technology developed at the University of Arizona, has been licensed to startup ElectroSonix. Dr. Russell Witte, BIO5 faculty and Medical Imaging professor at the UArizona College of Medicine-Tucson, developed the patented technology that provides improvements over current cardiac imaging technologies such as electroanatomical mapping, which provides low-resolution images that make it difficult to pinpoint the exact location of cardiac arrhythmias.
 
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In an interview with MD Magazine, Dr. Monica Kraft, Department of Medicine chair at the University of Arizona College of Medicine – Tucson, detailed her session on interpreting gender sex differences in lung disease, and what clinicians need to know when monitoring and caring for women at risk of asthma.
 
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Dr. Irving Kron, a BIO5 member, professor of surgery with the UA College of Medicine - Tucson, and senior associate vice president for UA Health Sciences, has been named the new contact principal investigator (PI) for the UA Health Sciences and Banner Health 'All of Us' research program and precision medicine initiative. In his new role, Dr. Kron will lead the multiple UA and Banner Health established PI leadership teams, which include a team led by fellow BIO5 member Dr. Eric Reiman.
 
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Obstructive sleep apnea is a common condition that has been associated with increased mortality. A UA physician-scientist has worked alongside BIO5 faculty members Drs. Raymond Woosley and Bonnie Lafleur, resulting in the awarding of a grant for research to analyze databases from the National Heart, Lung, and Blood Institute and Banner Health, to better understand the relationship between the sleep disorder and death.
 
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Thrombocytopenia, or HIT, is a deficiency of blood platelets, the cells that help blood clot. A team of UA College of Medicine-Tucson researchers including Associate Vice President and Director of the Center for Biomedical Informatics and Biostatistics at UA Health Sciences, Dr. Yves Lussier, is working in support of a new grant with the aim to identify predictive and early biomarkers for HIT.
 
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Although rare, common medications – including azithromycin and ondansetron – can contribute to prolonged heart-recharging intervals, which may lead to serious complications and hospital stays. To address this problem, UA researchers including College of Medicine-Phoenix professor Dr. Raymond Woosley, work to implement alerts embedded in patients’ electronic health records to assist health-care providers in mitigating sudden cardiac death.
 
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Researchers have found that emphysema may be a unique risk factor for aneurysm, potentially giving doctors another tool to identify people with aneurysms
 
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UA faculty, staff, students, alumni and friends come together to recognize exemplary engineers of past, present and future. Dr. Marvin Slepian, Associate Department Head of UA Biomedical Engineering, Arizona Center for Accelerated Biomedical Innovation founder and director, and BIO5 faculty, has been named the 2019 da Vinci Fellow, recognizing his research and teaching efforts in engineering, medicine, and entrepreneurship.
 
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Dr. Marvin Slepian, clinician-scientist-engineer-inventor and founding Director of the Arizona Center for Accelerated Biomedical Innovation, and Dr. Rod Wing, Bud Antle Endowed Chair Professor for Excellence in Agriculture in the School of Plant Sciences and Director of the Arizona Genomics Institute, both BIO5 members, have been named UA Regents Professors by the Arizona Board of Regents.
 
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The UA received a $1.1 million grant to study the biology underlying the connection between type 2 diabetes and cardiovascular disease. BIO5 member Dr. Yann Klimentidis is a lead researcher on the study, which will utilize publicly available health and genetic information from databases across the world, covering at least 650,000 people.
 
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Fitness trackers today can crunch a lot of useful health data. “We now have a multi-dimensional sensor which can capture a lot of information about how an individual moves through the world,” said Dr. Marvin Slepian, a BIO5 member and cardiologist.
 
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The Arizona Biomedical Research Commission has recognized 14 researchers from the UA Health Sciences to receive grant awards totaling more than $5.92 million. Eight of those researchers are BIO5 members, including Dr. Frank Duca, Dr. Louise Hecker, Dr. Tally Largent-Milnes, Dr. John Purdy, Dr. Benjamin Renquist, Dr. Todd Vanderah, Dr. Jun Wang, and Dr. Frederic Zenhausern.
 
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Avery Therapeutics, a startup company co-founded by BIO5 member and cardiologist at UA Sarver Heart Center, Dr. Steven Goldman, is most known for developing a tissue-engineered heart graft. Avery Therapeutics was recently honored during the "Buzz of Bio" awards as a winner in two separate categories.